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A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis

dc.contributor.authorShao, Wei
dc.contributor.authorPaul, Arghya
dc.contributor.authorAbbasi, Sana
dc.contributor.authorChahal, Parminder S.
dc.contributor.authorMena, Jimmy A.
dc.contributor.authorMontes, Johnny
dc.contributor.authorKamen, Amine
dc.contributor.authorPrakash, Satya
dc.date.accessioned2015-11-09T16:01:46Z
dc.date.available2015-11-09T16:01:46Z
dc.date.issued2012
dc.identifier.citationPrakash, Satya, Ms Wei Shao, Arghya Paul, Sana Abbasi, Parminder Chahal, Jimmy A. Mena, Johnny Montes, and Amine Kamen. "A Novel Polyethyleneimine-coated Adeno-associated Virus-like Particle Formulation for Efficient SiRNA Delivery in Breast Cancer Therapy: Preparation and in Vitro Analysis." International Journal of Nanomedicine IJN (2012): 1575. http://dx.doi.org/10.2147/IJN.S26891en_US
dc.identifier.urihttp://hdl.handle.net/1808/18852
dc.description.abstractSystemic delivery of small interfering RNA (siRNA) is limited by its poor stability and limited cell-penetrating properties. To overcome these limitations, we designed an efficient siRNA delivery system using polyethyleneimine-coated virus-like particles derived from adeno-associated virus type 2 (PEI-AAV2-VLPs).en_US
dc.publisherDove Medical Pressen_US
dc.rightsThis work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/
dc.subjectAdeno-associated virus type 2en_US
dc.subjectVirus-like particlesen_US
dc.subjectSmall interfering RNA deliveryen_US
dc.subjectBreast cancer therapyen_US
dc.subjectNanomedicineen_US
dc.titleA novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysisen_US
dc.typeArticle
kusw.kuauthorPaul, Arghya
kusw.kudepartmentChemical & Petroleum Engren_US
dc.identifier.doi10.2147/IJN.S26891
kusw.oaversionScholarly/refereed, publisher version
kusw.oapolicyThis item meets KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
Except where otherwise noted, this item's license is described as: This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php