Patterns of autism spectrum symptomatology in individuals with Down syndrome without comorbid autism spectrum disorder
dc.contributor.author | Channell, Marie Moore | |
dc.contributor.author | Phillips, B. Allyson | |
dc.contributor.author | Loveall, Susan J. | |
dc.contributor.author | Conners, Frances A. | |
dc.contributor.author | Bussanich, Paige M. | |
dc.contributor.author | Klinger, Laura Grofer | |
dc.date.accessioned | 2015-06-09T19:12:07Z | |
dc.date.available | 2015-06-09T19:12:07Z | |
dc.date.issued | 2014-04-07 | |
dc.identifier.citation | Channell, Marie Moore, B. Allyson Phillips, Susan Loveall, Frances Conners, Paige M. Bussanich, and Laura Grofer Klinger. "Patterns of Autism Spectrum Symptomatology in Individuals with Down Syndrome without Comorbid Autism Spectrum Disorder." Journal of Neurodevelopmental Disorders 7.5 (2015): n. pag. http://dx.doi.org/10.1186/1866-1955-7-5. | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/18053 | |
dc.description.abstract | BackgroundPrevalence estimates of autism spectrum disorder (ASD) in Down syndrome (DS) are highly varied. This variation is partly due to the difficulty of screening for and diagnosing comorbid ASD in individuals with a syndrome that carries its own set of social communicative and behavioral difficulties that are not well documented. The aim of this study was to identify the typical range of social communicative impairments observed in children, adolescents, and young adults with DS who do not have comorbid ASD. MethodsWe examined patterns of scores from the five subscales of the Social Responsiveness Scale (SRS) in 46 individuals with DS (ages 10–21 years) without comorbid ASD relative to the published normative sample. We also explored the correlations between SRS symptomatology and age, nonverbal cognition, and receptive language. ResultsSRS scores were elevated (i.e., more ASD symptoms endorsed), with mean scores falling into the clinically significant range. Analysis by subscale revealed a specific pattern, with Autistic Mannerisms and Social Cognition scores significantly more elevated than Social Communication scores, which were significantly more elevated than Social Awareness and Social Motivation scores. Correlations between SRS scores and the other measures varied by subscale. ConclusionsGeneral elevated ASD symptomatology on the SRS indicates the need for developing population-based norms specific to DS. The pattern of scores across subscales should inform clinicians of the typical range of behaviors observed in DS so that individuals with atypical patterns of behavior can be more easily identified and considered for a full ASD evaluation. | en_US |
dc.publisher | BioMed Central | en_US |
dc.relation.isversionof | http://www.jneurodevdisorders.com/content/7/1/5 | en_US |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Down syndrome | en_US |
dc.subject | Autism spectrum disorder | en_US |
dc.subject | Comorbidity | en_US |
dc.subject | Social communication | en_US |
dc.subject | Intellectual disablity | en_US |
dc.title | Patterns of autism spectrum symptomatology in individuals with Down syndrome without comorbid autism spectrum disorder | en_US |
dc.type | Article | |
kusw.kuauthor | Loveall, Susan | |
kusw.kudepartment | Life Span Institute | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.