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dc.contributor.authorFang, Jianwen
dc.contributor.authorDong, Yinghua
dc.contributor.authorSlamat-Miller, Nazila
dc.contributor.authorMiddaugh, C. Russell
dc.date.accessioned2014-04-17T13:41:08Z
dc.date.available2014-04-17T13:41:08Z
dc.date.issued2007-10-04
dc.identifier.citationFang, Jianwen, Yinghua Dong, Nazila Salamat-Miller, and C Russell Middaugh. 2008. “DB-PABP: A Database of Polyanion-Binding Proteins.” Nucleic Acids Research 36 (Database issue): D303–D306. http://dx.doi.org/10.1093/nar/gkm784
dc.identifier.urihttp://hdl.handle.net/1808/13532
dc.description.abstractThe interactions between polyanions (PAs) and polyanion-binding proteins (PABPs) have been found to play significant roles in many essential biological processes including intracellular organization, transport and protein folding. Furthermore, many neurodegenerative disease-related proteins are PABPs. Thus, a better understanding of PA/PABP interactions may not only enhance our understandings of biological systems but also provide new clues to these deadly diseases. The literature in this field is widely scattered, suggesting the need for a comprehensive and searchable database of PABPs. The DB-PABP is a comprehensive, manually curated and searchable database of experimentally characterized PABPs. It is freely available and can be accessed online at http://pabp.bcf.ku.edu/DB_PABP/. The DB-PABP was implemented as a MySQL relational database. An interactive web interface was created using Java Server Pages (JSP). The search page of the database is organized into a main search form and a section for utilities. The main search form enables custom searches via four menus: protein names, polyanion names, the source species of the proteins and the methods used to discover the interactions. Available utilities include a commonality matrix, a function of listing PABPs by the number of interacting polyanions and a string search for author surnames. The DB-PABP is maintained at the University of Kansas. We encourage users to provide feedback and submit new data and references.
dc.description.sponsorshipThis work was supported in part by K-INBRE Bioinformatics Core, NIH Grant P20 RR016475. Funding to pay the Open Access publication charges for this article was provided by Bioinformatics Core Facility at the University of Kansas.
dc.publisherOxford University Press
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by-nc/2.0/uk/
dc.titleDB-PABP: a database of polyanion-binding proteins
dc.typeArticle
kusw.kuauthorFang, Jianwen
kusw.kuauthorDong, Yinghua
kusw.kuauthorSalamat-Miller, Nazila
kusw.kuauthorMiddaugh, C. Russell
kusw.kudepartmentDepatment of Pharmaceutical Chemistry
kusw.oastatusna
dc.identifier.doi10.1093/nar/gkm784
kusw.oaversionScholarly/refereed, publisher version
kusw.oapolicyThis item does not meet KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.