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dc.contributor.authorLeCheminant, James D.
dc.contributor.authorSmith, Bryan K.
dc.contributor.authorWestman, Eric C.
dc.contributor.authorVernon, Mary C.
dc.contributor.authorDonnelly, Joseph E.
dc.date.accessioned2014-01-16T22:47:48Z
dc.date.available2014-01-16T22:47:48Z
dc.date.issued2010-06-01
dc.identifier.citationLeCheminant, James D, Bryan K Smith, Eric C Westman, Mary C Vernon, and Joseph E Donnelly. 2010. “Comparison of a Reduced Carbohydrate and Reduced Fat Diet for LDL, HDL, and VLDL Subclasses during 9-Months of Weight Maintenance Subsequent to Weight Loss.” Lipids in Health and Disease 9: 54. http://dx.doi.org/10.1186/1476-511X-9-54.
dc.identifier.urihttp://hdl.handle.net/1808/12756
dc.description.abstractObjectives: This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weight loss. Methods: Thirty-five (21 RC; 14 RF) overweight or obese middle-aged adults completed a 1-year weight management clinic. Participants met weekly for the first six months and bi-weekly thereafter. Meetings included instruction for diet, physical activity, and behavior change related to weight management. Additionally, participants followed a liquid very low-energy diet of ~2092 kJ per day for the first three months of the study. Subsequently, participants followed a dietary plan for nine months that targeted a reduced percentage of carbohydrate (~20%) or fat (~30%) intake and an energy intake level calculated to maintain weight loss. Lipid subclasses using NMR spectroscopy were analyzed prior to weight loss and at multiple intervals during weight maintenance. Results: Body weight change was not significantly different within or between groups during weight maintenance (p > 0.05). The RC group showed significant increases in mean LDL size, large LDL, total HDL, large and small HDL, mean VLDL size, and large VLDL during weight maintenance while the RF group showed increases in total HDL, large and small HDL, total VLDL, and large, medium, and small VLDL (p < 0.05). Group*time interactions were significant for large and medium VLDL (p > 0.05). Conclusion: Some individual lipid subclasses improved in both dietary groups. Large and medium VLDL subclasses increased to a greater extent across weight maintenance in the RF group.
dc.publisherBioMed Central
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.titleComparison of a reduced carbohydrate and reduced fat diet for LDL, HDL, and VLDL subclasses during 9-months of weight maintenance subsequent to weight loss
dc.typeArticle
kusw.kuauthorSmith, Bryan K.
kusw.kuauthorVernon, Mary C.
kusw.kuauthorDonnelly, Joseph E.
kusw.kudepartmentApplied Behavioral Science
kusw.oastatusfullparticipation
dc.identifier.doi10.1186/1476-511X-9-54
kusw.oaversionScholarly/refereed, publisher version
kusw.oapolicyThis item meets KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.