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Dissertations and Theses: Recent submissions
Now showing items 1421-1440 of 9900
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Modulation of Protein-Membrane Interactions by Lipids and Divalent Cations
(University of Kansas, 2020-05-31)The post-translational insertion of proteins into membranes is common in a number of biologically important processes, such as the cellular entry of bacterial toxins or regulation of apoptosis by the Bcl-2 family of proteins, ... -
Effect of Single Goal Versus Multiple Goal Dietary Interventions on Diet Quality Measures During Pregnancy
(University of Kansas, 2020-05-31)Background: During pregnancy, over 50% of women gain more than is recommended based on the National Academy of Medicine (NAM) guidelines. There is no consensus on dietary interventions to prevent excessive gestational ... -
Progesterone Receptor-Mediated Inhibition of Type I Interferon Signaling in Breast Cancer
(University of Kansas, 2020-05-31)Breast Cancer is an extremely heterogenous disease that is the second leading cause of cancer-related death among women in the United States. Of those diagnosed, the majority of breast cancers are hormone receptor positive, ... -
Late-Effect Symptoms, Tobacco and Alcohol Use, and Demoralization in Head and Neck Cancer Survivors
(University of Kansas, 2020-05-31)Worldwide, head and neck cancers are the sixth most common type of cancer and comprise the ninth most common forms of cancer in the United States. Estimates of U.S. adults diagnosed with head and neck cancer in 2017 exceeded ... -
Sepsis-Related Hospitalizations and Outcomes in HIV-Infected Veterans
(University of Kansas, 2020-05-31)Introduction: Sepsis continues to be a significant cause of hospitalizations and death especially among HIV-infected patients. However, little is known about the impact of sepsis hospitalizations, hospital mortality, and ... -
Resting Energy Expenditure in Athletes: Accuracy of Cunningham Prediction Equation Using DXA-Derived Fat Free Mass
(University of Kansas, 2020-05-31)Introduction: It is recommended to use the fat free mass (FFM) based Cunningham equation to accurately estimate resting energy expenditure (REE) in athletic populations. However, it is unknown if FFM derived from dual-energy ... -
Resting Energy Requirements in Overweight and Obese Adolescents: Do Prediction Equations Accurately Estimate Needs?
(University of Kansas, 2020-05-31)Background: Resting energy expenditure (REE) accounts for the largest portion of total energy expenditure (TEE) and is a valuable tool for clinicians to provide individualized energy needs recommendations. Accurate ... -
The Role of Stress on Black Women’s Food Motivation and Food Choice
(University of Kansas, 2020-05-31)The highest rates of obesity in the U.S. are among black women with a prevalence of 54.8%. Stress has been associated with differences in eating behaviors, such as emotional eating which can lead to obesity over time. ... -
Prelicensure Nursing Faculty Experiences with Debriefing Adjuncts in Simulation
(University of Kansas, 2020-05-31)The purpose of this study was to explore the experiences of faculty of prelicensure nursing students with debriefing and debriefing adjuncts in simulation. Debriefing adjuncts in simulation are active learning elements ... -
You Want Me To Document What: A Qualitative Descriptive Study of ED Nurses' Perceived Role in the Use of Electronic Healthcare Records in a Learning Healthcare System
(University of Kansas, 2020-05-31)Objective: Nurses are challenged with collecting and using information in the form of electronic healthcare records (EHR) data. Learning healthcare systems (LHS) are reliant on nurses collecting accurate patient information ... -
The Impact of Financial changes on Hospital Quality of Care: Evidence from State Medicaid Expansion
(University of Kansas, 2020-05-31)Understanding the relationship between hospital financial condition and quality of care is integral for policy makers and administrators as changes in financial condition can have drastic impacts on quality of care, ... -
Adherence to STARD 2015 Reporting Recommendations in Pathology
(University of Kansas, 2020-05-31)Diagnostic accuracy studies compare the performance of an index test against a reference standard test. The Standards for Reporting of Diagnostic Accuracy Studies (STARD) is a checklist of items that should be reported in ... -
Investigating Novel Inhibitors of Epithelial - Mesenchymal Transition (EMT) and Cancer Stem Cells (CSCs) in Pancreatic Cancer
(University of Kansas, 2020-05-31)Pancreatic cancer is the 4th leading cause of cancer-related death in the U.S. in 2019. The five-year survival rate for all stages combined is only 9%, which is the lowest among all types of cancer. The current chemotherapeutic ... -
Atypical Protein Kinase C iota in trophoblast lineage development and establishment of the maternal-fetal interface
(University of Kansas, 2020-05-31)Mammalian embryonic development depends on the indispensable contribution of a transient dynamic organ, the placenta, which supports the pregnancy during the entire gestational days. The placenta provides hormones to ... -
Neurons and Astrocytes Respond Differentially to Ketogenic Diet and Ketone Body Exposure: Implications for the Treatment of Alzheimer’s Disease.
(University of Kansas, 2020-08-31)Glucose hypometabolism and mitochondrial dysfunction are early deficits in Alzheimer’s disease (AD) brains that precede cognitive decline. Rescuing bioenergetic failure by providing an alternative fuel substrate is an ... -
Molecular and Structural Basis of Anthrax Lethal Toxin Pore Formation and Translocation
(University of Kansas, 2020-08-31)The morbidity and mortality of anthrax disease are associated with the anthrax toxin, which is generated by the gram-positive bacterium Bacillus anthracis. The anthrax toxin is an AB toxin composed of two components: an ... -
The impact of genetic differences, voluntary exercise, and thermal injury on chronic pain and comorbidities in psychologically-stressed mice.
(University of Kansas, 2020-05-31)An estimated 80% of Americans suffer from at least one stress-related symptom during a month’s time and the number is increasing year by year. Co-morbidity of pain and psychological disorders is very common, and both can ... -
T. S. Eliot’s Four Quartets and the Contemplation of Nature
(University of Kansas, 2020-05-31)This thesis reads T. S. Eliot’s Four Quartets as a dramatization of the progress of the spiritual life as elaborated within early Christianity, moving from praxis, where the soul engages in ascetical practice in an effort ... -
Spectacles of Horror: Approaching the Supernatural in Greek Tragedy
(University of Kansas, 2020-05-31)Belief in the power of the supernatural world to affect the world of the living permeates Greek tragedy. Contrary to traditional accounts of ancient Greece as a forebearer to modern Western culture, an exploration into ... -
Comparison of CD28 and ICAM-1 signal transduction pathways, earliest signaling events involving CD45 and effect of statins and low pH on T cell function
(University of Kansas, 2020-05-31)The multipotent naïve T cell of the immune system differentiates to mature, highly functional effector cells and differentiation is influenced by the microenvironment in which the T cell finds itself. Co-stimulatory ...