Overcoming the blood-brain barrier to taxane delivery for brain tumors and neurodegenerative diseases and brain tumors
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Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. Mackic, J. B.; Stins, M.; McComb, J.; Calero, M.; Ghiso, J.; Kim, K. S.; Yan, Shirley ShiDu; Stern, David M.; Schmidt, Ann Marie; Frangione, B.; Zlokovic, B. V. (American Society for Clinical Investigation, 1998-08-15)A soluble monomeric form of Alzheimer's amyloid-beta (1-40) peptide (sAbeta1-40) is present in the circulation and could contribute to neurotoxicity if it crosses the brain capillary endothelium, which comprises the ...
Delivering Molecules to the Brain using Blood-Brain Barrier Modulators: Mechanism of Action and Activity of Cyclic and Linear Peptides from E-cadherin Alaofi, Ahmed (University of Kansas, 2015-12-31)Delivering Molecules to the Brain using Blood-Brain Barrier Modulators: Mechanism of Action and Activity of Cyclic and Linear Peptides from E-cadherin Ahmed L. Alaofi The University of Kansas, 2015 The goals of this work ...