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    Delay Discounting in Lewis and Fischer 344 Rats: Implications for the Use of an Adjusting-amount Procedure to Detect Between-strain Differences

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    Stein_ku_0099M_11038_DATA_1.pdf (1.006Mb)
    Issue Date
    2010-07-21
    Author
    Stein, Jeff S.
    Publisher
    University of Kansas
    Format
    57 pages
    Type
    Thesis
    Degree Level
    M.A.
    Discipline
    Applied Behavioral Science
    Rights
    This item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
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    Abstract
    Strain-related behavioral differences may facilitate investigation of the genetic and neurochemical determinants of delay discounting. Previous researchers report that Lewis rats make more impulsive choices than Fischer 344 rats, although the size of this difference appears to vary depending on the procedure used. Additionally, researchers using a rapid-determination adjusting-amount procedure (in which reinforcer delay is manipulated between sessions regardless of within-session trend or variability) report no difference in delay discounting between strains. The present study was designed to compare degree of delay discounting between strains using a steady-state version of the adjusting-amount procedure in which delay was manipulated between conditions following satisfaction of experimenter-defined stability criteria. Using such a procedure, Lewis rats exhibited modestly steeper delay discounting for food reinforcers than Fischer 344 rats. However, under the rapid-determination procedure, no difference was observed; further, among Lewis rats, discounting was not correlated between assessments. These results suggest the rapid-determination procedure may be insensitive to modest differences otherwise detected using steady-state methods. Differences in discounting are discussed in the context of neurochemical and neuroendocrine differences between strains.
    URI
    http://hdl.handle.net/1808/6720
    Collections
    • Applied Behavioral Science Dissertations and Theses [149]
    • Theses [3768]

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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