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    Relationship between Bilirubin and Auditory Function in Premature Neonates

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    Bargen_ku_0099D_10775_DATA_1.pdf (4.152Mb)
    Issue Date
    2010-01-01
    Author
    Bargen, Gabriel Anne
    Publisher
    University of Kansas
    Format
    136 pages
    Type
    Dissertation
    Degree Level
    Ph.D.
    Discipline
    Hearing and Speech
    Rights
    This item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
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    Abstract
    Research has shown hyperbilirubinemia is more prevalent in preterm infants than in term infants. Hyperbilirubin is toxic to the central nervous system and may cause neurological impairments in newborns with the most consistent impairment being auditory dysfunction. However, national guidelines are needed which address bilirubin levels in premature infants. The study objective was to determine the relationship between bilirubin levels and auditory function in preterm infants. The auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) were prospectively investigated in premature infants while monitoring total serum bilirubin (TSB) levels. Ten subjects with mean gestational age of 31.5 weeks and mean peak-TSB of 7.91 mg/dL were enrolled. The posthoc peak-TSB to birth weight ratio placed all subjects in the control group. Spearman's correlation coefficient indicated no significant correlation between peak-TSB levels and auditory function. Further research with hyperbilirubinemia subjects is needed to determine when preterm infants' auditory function is affected.
    URI
    http://hdl.handle.net/1808/6410
    Collections
    • Dissertations [4660]
    • Speech-Language-Hearing Dissertations and Theses [75]

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    785-864-8983
    KU Libraries
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    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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