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    Cortical and Subcortical Correlates of Ororhythmic Behaviors

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    Estep_ku_0099D_10637_DATA_1.pdf (5.239Mb)
    Issue Date
    2009-12-09
    Author
    Estep, Meredith Emslie
    Publisher
    University of Kansas
    Format
    196 pages
    Type
    Dissertation
    Degree Level
    Ph.D.
    Discipline
    Neurosciences
    Rights
    This item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
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    Abstract
    Although the healthy adult possesses a large repertoire of coordinative strategies for oromotor behaviors, a range of nonverbal, speech-like movements including cyclic jaw motion and lip pursing can be observed during speech. The extent of overlap among sensorimotor speech and nonspeech central neural correlates is unknown. The purpose of this study was to determine the spatial extent of unique and shared neural bases subserving task- and rate-specific ororhythmic behaviors utilizing a randomized block design fMRI study with an audiovisual motor stimulus paradigm to record neural correlates of suck and unvoiced syllabic speech performed at 1 or 3 Hz by a group of healthy adults. A functionally defined region of interest analysis provided (1) descriptive analysis of individual clusters, and (2) quantitative analysis of the extent of activation differences between conditions. Both factors (task and rate) were shown to significantly affect BOLD signal changes at the cortical, subcortical, and brainstem levels.
    URI
    http://hdl.handle.net/1808/6174
    Collections
    • KU Med Center Dissertations and Theses [464]
    • Dissertations [4473]

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    785-864-8983
    KU Libraries
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    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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