Show simple item record

dc.contributor.advisorKelly, John K
dc.contributor.advisorOrive, Maria E
dc.contributor.authorMarriage, Tara N.
dc.date.accessioned2010-03-18T03:55:02Z
dc.date.available2010-03-18T03:55:02Z
dc.date.issued2009-08-24
dc.date.submitted2009
dc.identifier.otherhttp://dissertations.umi.com/ku:10544
dc.identifier.urihttp://hdl.handle.net/1808/5949
dc.description.abstractMy dissertation addresses mutation and complex mating systems (models of mating systems that include outcrossing, selfing, and asexual reproduction) in three distinct chapters. Chapter 2 discusses the direct estimation of mutation rates for di-nucleotide microsatellite markers in the model genetic organism, Arabidopsis thaliana. Chapter 3 describes an empirical study that estimates quantitative genetic variance components, genetic diversity, and inbreeding depression/inbreeding load for a predominately asexual population of Mimulus guttatus. This study also fits different evolutionary models to the empirical data to determine which model best describes the population. Chapter 4 is a theoretical investigation of the effects asexual reproduction, outcrossing and selfing on the average number of deleterious mutations per gamete and inbreeding load for infinite and finite populations. The study utilizes both Infinite (an infinite number of genetic loci and an infinite population size) and Finite (a small number of genetic loci and a variety of small population sizes) computer simulations. These simulations incorporate different meiotic and mitotic mutation rates, varying degrees of dominance and differing strengths of selection.
dc.format.extent126 pages
dc.language.isoEN
dc.publisherUniversity of Kansas
dc.rightsThis item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
dc.subjectBiology
dc.subjectGenetics
dc.subjectBotany
dc.subjectArabidopsis
dc.subjectAsexual reproduction
dc.subjectGenetic load
dc.subjectInbreeding load
dc.subjectMicrosatellite mutation rate
dc.subjectMimulus
dc.titleMutation, asexual reproduction and genetic load: A study in three parts
dc.typeDissertation
dc.contributor.cmtememberKelly, John K
dc.contributor.cmtememberOrive, Maria E
dc.contributor.cmtememberAlexander, Helen
dc.contributor.cmtememberMort, Mark E
dc.contributor.cmtememberTimmons, Lisa
dc.thesis.degreeDisciplineEcology & Evolutionary Biology
dc.thesis.degreeLevelPh.D.
kusw.oastatusna
kusw.oapolicyThis item does not meet KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record