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    Reliability and validity of the Premie-Neuro in detecting early neurodevelopmental delay and disability in preterm infants

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    Issue Date
    2009-08-18
    Author
    Gagnon, Kendra
    Publisher
    University of Kansas
    Format
    166 pages
    Type
    Dissertation
    Degree Level
    Ph.D.
    Discipline
    Physical Therapy & Rehabilitation Sciences
    Rights
    This item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
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    Abstract
    There are few reliable and valid methods available for clinicians to assess the functional neurological status of the preterm infant. In this study, we set out to determine whether the Premie-Neuro, a new standardized clinical neurological assessment for preterm infants, is a reliable, valid, and predictive tool. Thirty-four preterm infants were assessed twice, no more than 72 hours apart, using the Premie-Neuro. One assessment per infant was observed and scored by a second examiner. Infants continued to be administered the Premie-Neuro weekly through 37 weeks post-menstrual age or discharge from the neonatal intensive care unit (NICU). At discharge, infants' medical charts were reviewed to determine medical risk factors for neurodevelopmental delay. Follow-up testing was conducted at term adjusted age using the NeoNeuro and at 3 months adjusted age using the Infanib and Alberta Infant Motor Scale. Data were analyzed to determine interrater and test-retest reliabilities, construct validity, and predictive validity of the Premie-Neuro. Premie-Neuro raw scores--particularly those obtained close to NICU discharge--were reliable, valid, and predictive of performance at term and 3 months adjusted age. Premie-Neuro classifications (abnormal, questionable, or normal) based on the Premie-Neuro authors' recommended raw score cut-points were generally not reliable, valid, or predictive. After 34 weeks post-menstrual age (PMA), using a discharge Premie-Neuro raw score cut-point of 99 may be considered low-risk. Infants with scores ranging from 90-99 should be closely monitored to ensure that neurological abnormalities do not emerge. Using these criteria, the Premie-Neuro may be used to identify at-risk babies who will benefit from specialized services and/or close post-term follow-up. This has potential to improve effectiveness, efficiency, and outcomes of early supports and services provided to preterm babies.
    URI
    http://hdl.handle.net/1808/5944
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    • KU Med Center Dissertations and Theses [464]
    • Dissertations [4321]

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    KU Libraries
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    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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