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Temporary: Recent submissions
Now showing items 1-20 of 21
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Combining the Benefits of Biotin–Streptavidin Aptamer Immobilization with the Versatility of Ni-NTA Regeneration Strategies for SPR
(MDPI, 2024-04-27)The high affinity of the biotin–streptavidin interaction has made this non-covalent coupling an indispensable strategy for the immobilization and enrichment of biomolecular affinity reagents. However, the irreversible ... -
Potent small molecule inhibitors against the 3C protease of foot-and-mouth disease virus
(American Society for Microbiology, 2024-03-11)Foot-and-mouth disease (FMD) is one of the most devastating diseases of livestock which can cause significant economic losses, especially when introduced to FMD-free countries. FMD virus (FMDV) belongs to the family ... -
Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training
(The Physiological Society, 2024-04-21)Exercise‐induced muscle adaptations vary based on exercise modality and intensity. We constructed a signalling network model from 87 published studies of human or rodent skeletal muscle cell responses to endurance or ... -
Broadscale spatial synchrony in a West Nile virus mosquito vector across multiple timescales
(Nature Research, 2024-05-30)Insects often exhibit irruptive population dynamics determined by environmental conditions. We examine if populations of the Culex tarsalis mosquito, a West Nile virus (WNV) vector, fluctuate synchronously over broad spatial ... -
Comparison of vertical jump and sprint performances between 3 × 3 and 5 × 5 elite professional male basketball players
(Frontiers Media, 2024-05-10)Given its fast-growing popularity and unique on-court competitive demands, 3 × 3 basketball has captured a considerable amount of attention over recent years. However, unlike research focused on studying 5 × 5 basketball ... -
Everyday Challenges for Individuals Aging With Vision Impairment: Technology Implications
(Oxford University Press, 2023-12-20)Background and Objectives There are growing numbers of older adults with long-term vision impairment who are likely to experience everyday activity challenges from their impairment in conjunction with age-related changes. ... -
Physiognomy datasets across two sub-montane tropical forests: Bakossi National Park and Mt. Nlonako in the continental Cameroon mountains
(Elsevier, 2024-04-25)The submontane forests in the Congo Basin have not been studied sufficiently in terms of floristic diversity, biomass, and geographic distribution. The region's lack of resources and rugged terrain are among the barriers ... -
The Moderation Effect of Approach Motivation Between Schizotypy and Creative Ideational Behavior
(Dovepress, 2024-05-09)Introduction The schizotypy-creativity link has been studied from different perspectives over the past few decades, yet the results of this relationship are inconsistent in the literature. Previous studies have suggested ... -
Effects of the Flying Start on Estimated Short Sprint Profiles Using Timing Gates
(MDPI, 2024-05-01)Short sprints are predominantly assessed using timing gates and analyzed through parameters of the mono-exponential equation, including estimated maximal sprinting speed (MSS) and relative acceleration (TAU), derived maximum ... -
Increased Risk of Breakthrough SARS-CoV-2 Infections in Patients with Colorectal Cancer: A Population-Based Propensity-Matched Analysis
(MDPI, 2024-04-24)Background/Objectives: This study aimed to investigate the association between colorectal cancer (CRC) and the risk of breakthrough respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated patients with CRC. ... -
The MAB-5/Hox family transcription factor is important for Caenorhabditis elegans innate immune response to Staphylococcus epidermidis infection
(Oxford University Press, 2024-03-13)Innate immunity functions as a rapid defense against broad classes of pathogenic agents. While the mechanisms of innate immunity in response to antigen exposure are well-studied, how pathogen exposure activates the innate ... -
Investigating the stretch-shortening cycle fatigue response to a high-intensity stressful phase of training in collegiate men's basketball
(Frontiers Media, 2024-04-18)Introduction While using force-plate derived measures of vertical jump performance, reflective of stretch-shortening-cycle (SSC) efficiency is common practice in sport science, there is limited evidence as to which tests ... -
MRI Accurately Predicts Quadrupled Semitendinosus Autograft Size Using Posterior Hamstring Harvest for ACL Reconstruction
(Elsevier, 2024-04-08)Purpose To determine the effectiveness of preoperative magnetic resonance imaging (MRI) measurements of the cross-sectional area (CSA) of the semitendinosus tendon in predicting the intraoperative quadrupled semitendinosus ... -
Development of a nano-emulsion based multivalent protein subunit vaccine against Pseudomonas aeruginosa
(Frontiers Media, 2024-04-18)Pseudomonas aeruginosa (Pa) is an opportunistic bacterial pathogen responsible for severe hospital acquired infections in immunocompromised and elderly individuals. Emergence of increasingly drug resistant strains and the ... -
The Italian food environment may confer protection from hyper-palatable foods: evidence and comparison with the United States
(Frontiers Media, 2024-04-17)Background Multi-national food corporations may saturate country-level food systems with hyper-palatable foods. However, the degree to which global food corporations have been integrated into country-level food systems ... -
N6-methyladenosine modification of a parvovirus-encoded small noncoding RNA facilitates viral DNA replication through recruiting Y-family DNA polymerases
(PNAS, 2024-06-14)Human bocavirus 1 (HBoV1) is a human parvovirus that causes lower respiratory tract infections in young children. It contains a single-stranded (ss) DNA genome of ~5.5 kb that encodes a small noncoding RNA of 140 nucleotides ... -
Changing the Paradigm in Prognostic Breast Cancer Testing Based on Extracellular Vesicles
(US Department of Health and Human Services, 2023-06-22)Women with early-stage breast cancer have several options for genomic tests including Oncotype DX®, MammaPrint®, and Prosigna® that can estimate risk of distant recurrence and help determine whether they will benefit from ... -
A Combined LC-MS and Immunoassay Approach to Characterize Preservative-Induced Destabilization of Human Papillomavirus Virus-like Particles Adsorbed to an Aluminum-Salt Adjuvant
(MDPI, 2024-07-02)During the multi-dose formulation development of recombinant vaccine candidates, protein antigens can be destabilized by antimicrobial preservatives (APs). The degradation mechanisms are often poorly understood since ... -
Evaluating the Compatibility of New Recombinant Protein Antigens (Trivalent NRRV) with a Mock Pentavalent Combination Vaccine Containing Whole-Cell Pertussis: Analytical and Formulation Challenges
(MDPI, 2024-06-03)Introducing new recombinant protein antigens to existing pediatric combination vaccines is important in improving coverage and affordability, especially in low- and middle-income countries (LMICs). This case-study highlights ... -
Population pharmacokinetic analysis of enrofloxacin and its active metabolite ciprofloxacin after intravenous injection to cats with reduced kidney function
(Wiley Open Access, 2023-09-20)Background It is unknown if enrofloxacin accumulates in plasma of cats with reduced kidney function. Hypothesis To determine if enrofloxacin and its active metabolite ciprofloxacin have reduced clearance in azotemic ...