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dc.contributor.advisorMalinakova, Helena C
dc.contributor.authorHershberger, John Charles
dc.date.accessioned2009-06-18T20:14:30Z
dc.date.available2009-06-18T20:14:30Z
dc.date.issued2009-01-01
dc.date.submitted2009
dc.identifier.otherhttp://dissertations.umi.com/ku:10302
dc.identifier.urihttp://hdl.handle.net/1808/5251
dc.description.abstractWhile reactions with organopalladium intermediates often give useful organic products, little is known about how the ligand sphere impacts the reactivity of these intermediates. To explore the interactions between the auxiliary ligand and the other substitutents on the metal center, we performed synthetic and structural studies on both polymer-bound palladacycles and a new organometallic scaffold, the palladapyrrolidinone. In the case of palladacycles on solid-phase, we observed that the precise characteristics of the polymer-bound ligand had a large impact on the reactivity of the complex. In the case of the palladapyrrolidinones, we observed that the shape and size of the ligand sphere had a large impact on the diastereoselective formation of a sp3-C stereocenter bound to a palladium center. We found that a chiral non-racemic ligand had little impact on the stereoselectivity. In conclusion, the ligand sphere has a distinct impact on both the reactivity and stereoselectivity of reactions involving palladacycles.
dc.format.extent428 pages
dc.language.isoEN
dc.publisherUniversity of Kansas
dc.rightsThis item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
dc.subjectOrganic chemistry
dc.subjectInorganic chemistry
dc.subjectMechanisms
dc.subjectOrganometallic
dc.subjectPalladacycle
dc.subjectPathway
dc.subjectStereoinduction
dc.titlePalladacycles with Palladium-Bonded Stereogenic Carbons: Tools for Exploring Reaction Pathways in Organometallic Chemistry
dc.typeDissertation
dc.contributor.cmtememberMalinakova, Helena C.
dc.contributor.cmtememberBarybin, Mikhail V.
dc.contributor.cmtememberGivens, Richard S
dc.contributor.cmtememberTunge, Jon A
dc.contributor.cmtememberPrisinzano, Thomas E.
dc.thesis.degreeDisciplineChemistry
dc.thesis.degreeLevelPh.D.
kusw.oastatusna
kusw.oapolicyThis item does not meet KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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