Light-driven Catalysis in Decarboxylative Small Molecule Functionalization

Abstract

Herein, the development and mechanistic elucidation of light-driven decarboxylative processes for the installation of olefins is described. The primary focus has been to devise methodology that allows for the installation of highly versatile functionalities and the synthesis of synthetically valuable building-blocks while adhering to the principles of green chemistry. This has been accomplished through the development of decarboxylative transformations that utilize light-driven catalysis. Through these developments, new approaches to olefin installation that improve upon the utility, economy, and environmental impact of traditional methods have been realized. In addition, new insights into catalyst reactivity have advanced the understanding of the reaction mechanisms and will ideally aid in further developments in the field.