Abstract
Seizure is a rare but documented adverse event associated with ampicillin, which is one of the most commonly used antibiotics used in pediatrics. We report a case of a 4-month-old male infant with Haemophilus influenzae type A meningitis that experienced recurrent tonic-clonic seizures, possibly secondary to ampicillin treatment. After ampicillin administration was withdrawn and antiepileptic agents were administered, the seizures resolved, improving the patient’s clinical status rapidly. This case report adds to the growing body of literature on ampicillin-induced seizures.
Description
A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.
Citation
William Wesson, Rachel Stetson, Hammad Ganatra & Shawn Sood (2023) Ampicillin-induced seizures in a 4-month-old with bacterial meningitis: a case report, Toxicology Communications, 7:1, 2212539, DOI: 10.1080/24734306.2023.2212539