ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated. If you have any questions, please contact Marianne Reed at mreed@ku.edu .

Show simple item record

N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers

dc.contributor.authorShinde, Anand H.
dc.contributor.authorNagamalla, Someshwar
dc.contributor.authorSathyamoorthi, Shyam
dc.date.accessioned2023-06-13T15:38:56Z
dc.date.available2023-06-13T15:38:56Z
dc.date.issued2020-05-17
dc.identifier.citationShinde, A.H., Nagamalla, S. & Sathyamoorthi, S. N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers. Med Chem Res 29, 1223–1229 (2020). https://doi.org/10.1007/s00044-020-02556-xen_US
dc.identifier.urihttps://hdl.handle.net/1808/34348
dc.description.abstractThis communication describes a variety of nucleophilic ring openings of N-arylated oxathiazinane heterocycles. We find that this reaction is compatible with phenoxides, naphthoxides, and thiolates and allows for the rapid assembly of N-aryl-amino ethers and N-aryl-amino thioethers. Fourteen examples are shown and a mechanistic pathway is hypothesized.en_US
dc.publisherSpringeren_US
dc.rightsCopyright © 2020, Springer Science Business Media, LLC, part of Springer Nature.en_US
dc.subjectNucleophileen_US
dc.subjectSulfamateen_US
dc.subjectOxathiazinaneen_US
dc.subjectAza-Wackeren_US
dc.titleN-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethersen_US
dc.typeArticleen_US
kusw.kuauthorShinde, Anand H.
kusw.kuauthorNagamalla, Someshwar
kusw.kuauthorSathyamoorthi, Shyam
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1007/s00044-020-02556-xen_US
dc.identifier.orcidhttps://orcid.org/0000-0003-4705-7349en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC10191371en_US
dc.rights.accessrightsopenAccessen_US


Files in this item

Thumbnail
Name:
Shinde_2020.pdf
Size:
772.0Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record