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Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability
dc.contributor.author | Morgan, Aaron | |
dc.contributor.author | LeGresley, Sarah | |
dc.contributor.author | Fischer, Christopher | |
dc.date.accessioned | 2022-01-11T20:28:50Z | |
dc.date.available | 2022-01-11T20:28:50Z | |
dc.date.issued | 2020-12-23 | |
dc.identifier.citation | Morgan, A.; LeGresley, S.; Fischer, C. Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability. Int. J. Mol. Sci. 2021, 22, 76. https://doi.org/10.3390/ijms22010076 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/32392 | |
dc.description.abstract | The packaging of the eukaryotic genome into chromatin regulates the storage of genetic information, including the access of the cell’s DNA metabolism machinery. Indeed, since the processes of DNA replication, translation, and repair require access to the underlying DNA, several mechanisms, both active and passive, have evolved by which chromatin structure can be regulated and modified. One mechanism relies upon the function of chromatin remodeling enzymes which couple the free energy obtained from the binding and hydrolysis of ATP to the mechanical work of repositioning and rearranging nucleosomes. Here, we review recent work on the nucleosome mobilization activity of this essential family of molecular machines. | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Copyright: 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Chromatin remodelers | en_US |
dc.subject | Nucleosome repositioning | en_US |
dc.subject | Molecular machines | en_US |
dc.subject | Enzyme mechanism | en_US |
dc.title | Remodeler Catalyzed Nucleosome Repositioning: Influence of Structure and Stability | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Morgan, Aaron | |
kusw.kuauthor | LeGresley, Sarah | |
kusw.kuauthor | Fischer, Christopher | |
kusw.kudepartment | Physics and Astronomy | en_US |
dc.identifier.doi | 10.3390/ijms22010076 | en_US |
dc.identifier.orcid | https://orcid.org/ 0000-0002-7576-7295 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC7793527 | en_US |
dc.rights.accessrights | openAccess | en_US |