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Outcomes of intraoperative ultrasound for endoscopic endonasal transsphenoidal pituitary surgery in adenomas with parasellar extension
dc.contributor.author | Domino, Joseph S. | |
dc.contributor.author | Gattozzi, Domenico A. | |
dc.contributor.author | Jack, Megan | |
dc.contributor.author | Carroll, Melissa | |
dc.contributor.author | Harn, Nick | |
dc.contributor.author | Beahm, D. David | |
dc.contributor.author | Chamoun, Roukoz | |
dc.date.accessioned | 2021-06-23T17:09:09Z | |
dc.date.available | 2021-06-23T17:09:09Z | |
dc.date.issued | 2021-04-18 | |
dc.identifier.citation | Joseph S. Domino, Domenico A. Gattozzi, Megan Jack, Melissa Carroll, Nick Harn, D. David Beahm, Roukoz Chamoun, Outcomes of intraoperative ultrasound for endoscopic endonasal transsphenoidal pituitary surgery in adenomas with parasellar extension, Interdisciplinary Neurosurgery, Volume 25, 2021, https://doi.org/10.1016/j.inat.2021.101225. | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/31697 | |
dc.description | A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml. | en_US |
dc.description.abstract | Background Pituitary adenomas with parasellar extension present a technical challenge for adequate visualization and gross total resection (GTR). The endoscope improves identification of parasellar extension, however, additional intraoperative imaging adjuncts can further augment visualization. Intraoperative ultrasound (iUS) may provide a viable and cost-effective solution for intraoperative imaging. We sought to assess the ability of intraoperative ultrasound to predict extent of resection on 3-month postoperative magnetic resonance imaging (MRI) in pituitary adenomas with parasellar extension.Methods Twenty consecutive patients undergoing endoscopic endonasal transsphenoidal surgery for pituitary adenomas with the assistance of intraoperative ultrasound were prospectively collected. Intraoperative ultrasound findings were recorded during each case. 3-month postoperative MRI studies were reviewed in a blinded fashion to assess for residual tumor and compared with the intraoperative ultrasound findings.Results Median preoperative Knosp grade was 2. Cavernous sinus invasion was encountered intraoperatively in 3 patients, all of whom were Knosp grade 3 preoperatively. Median operative time was 152 min. Based on iUS findings, 17 patients were expected to have a GTR while 3 patients underwent subtotal resection. 18 patients completed a 3-month postoperative MRI. The iUS and MRI findings were concordant in 16 cases (88.9%) with only two instances of discordance.Conclusion Intraoperative ultrasound can reliably predict tumor resection as assessed by 3-month postoperative MRI in pituitary adenomas with parasellar extension. Image capture and interpretation may vary based on operator experience. Ultrasound provides reliable immediate assessment of extent of resection, identification of normal pituitary gland and other important neurovascular structures. | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | © 2021 The Author(s). Published by Elsevier B.V. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
dc.subject | Endoscopic transsphenoidal | en_US |
dc.subject | Imaging | en_US |
dc.subject | Intraoperative ultrasound | en_US |
dc.subject | Parasellar extension | en_US |
dc.subject | Pituitary surgery | en_US |
dc.title | Outcomes of intraoperative ultrasound for endoscopic endonasal transsphenoidal pituitary surgery in adenomas with parasellar extension | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Domino, Joseph S. | |
kusw.kuauthor | Gattozzi, Domenico A. | |
kusw.kuauthor | Carroll, Melissa | |
kusw.kuauthor | Harn, Nick | |
kusw.kuauthor | Beahm, D. David | |
kusw.kuauthor | Chamoun, Roukoz | |
kusw.kudepartment | KU Medical Center | en_US |
dc.identifier.doi | 10.1016/j.inat.2021.101225 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess | en_US |
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