NDM-1 carbapenemase in Acinetobacter baumannii sequence type 32 in Ecuador

Villacís, J.E.; Bovera, M.; Romero-Alvarez, D.; Cornejo, F.; Albán, V.; Trueba, G.; Dorn, H.F.; Reyes, J.A.

dc.contributor.author	Villacís, J.E.
dc.contributor.author	Bovera, M.
dc.contributor.author	Romero-Alvarez, D.
dc.contributor.author	Cornejo, F.
dc.contributor.author	Albán, V.
dc.contributor.author	Trueba, G.
dc.contributor.author	Dorn, H.F.
dc.contributor.author	Reyes, J.A.
dc.date.accessioned	2020-11-24T16:10:32Z
dc.date.available	2020-11-24T16:10:32Z
dc.date.issued	2019-03-08
dc.identifier.citation	Villacís, J. E., Bovera, M., Romero-Alvarez, D., Cornejo, F., Albán, V., Trueba, G., Dorn, H. F., & Reyes, J. A. (2019). NDM-1 carbapenemase in Acinetobacter baumannii sequence type 32 in Ecuador. New microbes and new infections, 29, 100526. https://doi.org/10.1016/j.nmni.2019.100526	en_US
dc.identifier.uri	http://hdl.handle.net/1808/30911
dc.description	This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.	en_US
dc.description.abstract	Objectives To describe a clinical case of Acinetobacter baumannii sequence type (ST) 32 harbouring a New Delhi metallo-β-lactamase (NDM) in Ecuador. Methods We used multilocus sequence typing (MLST) to confirm the bacterial species and the sequence type of an A. baumannii isolate. We used synergy with the imipenem–EDTA disc method and the carbapenem inactivation method (CIM) to determine carbapenemase production; the presence of a carbapenemase gene was confirmed by PCR amplification and amplicon sequencing. Results Molecular characterization revealed the presence of A. baumannii ST32 harbouring the blaNDM-1 gene in Ecuador. The blaNDM-1 gene was isolated through PCR and amplified from a purified plasmid. Conclusions To the best of our knowledge, this is the first report of A. baumannii ST32 harbouring the blaNDM-1 gene.	en_US
dc.publisher	Elsevier	en_US
dc.rights	© 2019 The Author(s). Published by Elsevier Ltd.	en_US
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	en_US
dc.subject	Acinetobacter baumannii	en_US
dc.subject	Antibiotic resistance	en_US
dc.subject	blaNDM-1	en_US
dc.subject	MSLT	en_US
dc.subject	Sequence type 32	en_US
dc.title	NDM-1 carbapenemase in Acinetobacter baumannii sequence type 32 in Ecuador	en_US
dc.type	Article	en_US
kusw.kuauthor	Romero-Alvarez, D.
kusw.kudepartment	Ecology & Evolutionary Biology	en_US
kusw.kudepartment	Biodiversity Institute	en_US
dc.identifier.doi	10.1016/j.nmni.2019.100526	en_US
kusw.oaversion	Scholarly/refereed, publisher version	en_US
kusw.oapolicy	This item meets KU Open Access policy criteria.	en_US
dc.identifier.pmid	PMC6438911	en_US
dc.rights.accessrights	openAccess	en_US

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