Assessing Monkeypox Virus Prevalence in Small Mammals at the Human-Animal Interface in the Democratic Republic of the Congo
dc.contributor.author | Doty, Jeffrey B. | |
dc.contributor.author | Malekani, Jean M. | |
dc.contributor.author | Kalemba, Lem's N. | |
dc.contributor.author | Stanley, William T. | |
dc.contributor.author | Monroe, Benjamin P. | |
dc.contributor.author | Nakazawa, Yoshinori U. | |
dc.contributor.author | Mauldin, Matthew R. | |
dc.contributor.author | Bakambana, Trésor L. | |
dc.contributor.author | Dja Liyandja, Tobit Liyandja | |
dc.contributor.author | Braden, Zachary H. | |
dc.contributor.author | Wallace, Ryan M. | |
dc.contributor.author | Malekani, Divin V. | |
dc.contributor.author | McCollum, Andrea M. | |
dc.contributor.author | Gallardo-Romero, Nadia | |
dc.contributor.author | Kondas, Ashley | |
dc.contributor.author | Peterson, A. Townsend | |
dc.contributor.author | Osorio, Jorge E. | |
dc.contributor.author | Rocke, Tonie E. | |
dc.contributor.author | Karem, Kevin L. | |
dc.contributor.author | Emerson, Ginny L. | |
dc.contributor.author | Carroll, Darin S. | |
dc.date.accessioned | 2018-11-15T18:17:05Z | |
dc.date.available | 2018-11-15T18:17:05Z | |
dc.date.issued | 2017-10-03 | |
dc.identifier.citation | Doty, J.B.; Malekani, J.M.; Kalemba, L.N.; Stanley, W.T.; Monroe, B.P.; Nakazawa, Y.U.; Mauldin, M.R.; Bakambana, T.L.; Liyandja Dja Liyandja, T.; Braden, Z.H.; Wallace, R.M.; Malekani, D.V.; McCollum, A.M.; Gallardo-Romero, N.; Kondas, A.; Peterson, A.T.; Osorio, J.E.; Rocke, T.E.; Karem, K.L.; Emerson, G.L.; Carroll, D.S. Assessing Monkeypox Virus Prevalence in Small Mammals at the Human–Animal Interface in the Democratic Republic of the Congo. Viruses 2017, 9, 283. | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/27361 | |
dc.description.abstract | During 2012, 2013 and 2015, we collected small mammals within 25 km of the town of Boende in Tshuapa Province, the Democratic Republic of the Congo. The prevalence of monkeypox virus (MPXV) in this area is unknown; however, cases of human infection were previously confirmed near these collection sites. Samples were collected from 353 mammals (rodents, shrews, pangolins, elephant shrews, a potamogale, and a hyrax). Some rodents and shrews were captured from houses where human monkeypox cases have recently been identified, but most were trapped in forests and agricultural areas near villages. Real-time PCR and ELISA were used to assess evidence of MPXV infection and other Orthopoxvirus (OPXV) infections in these small mammals. Seven (2.0%) of these animal samples were found to be anti-orthopoxvirus immunoglobulin G (IgG) antibody positive (six rodents: two Funisciurus spp.; one Graphiurus lorraineus; one Cricetomys emini; one Heliosciurus sp.; one Oenomys hypoxanthus, and one elephant shrew Petrodromus tetradactylus); no individuals were found positive in PCR-based assays. These results suggest that a variety of animals can be infected with OPXVs, and that epidemiology studies and educational campaigns should focus on animals that people are regularly contacting, including larger rodents used as protein sources. | en_US |
dc.publisher | MDPI | en_US |
dc.rights | © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Habitat analysis | en_US |
dc.subject | Human-animal interface | en_US |
dc.subject | Monkeypox | en_US |
dc.subject | Orthopoxviruses | en_US |
dc.subject | Serology | en_US |
dc.subject | Small mammals | en_US |
dc.subject | Wildlife | en_US |
dc.title | Assessing Monkeypox Virus Prevalence in Small Mammals at the Human-Animal Interface in the Democratic Republic of the Congo | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Peterson, A. Townsend | |
kusw.kudepartment | Biodiversity Institute | en_US |
dc.identifier.doi | 10.3390/v9100283 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess | en_US |
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Except where otherwise noted, this item's license is described as: © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).