KUKU

KU ScholarWorks

  • myKU
  • Email
  • Enroll & Pay
  • KU Directory
    • Login
    View Item 
    •   KU ScholarWorks
    • Dissertations and Theses
    • Dissertations
    • View Item
    •   KU ScholarWorks
    • Dissertations and Theses
    • Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Cognition in Older Adult MS Patients Compared to Healthy Controls and aMCI Patients

    Thumbnail
    View/Open
    Roth_ku_0099D_14742_DATA_1.pdf (841.4Kb)
    Issue Date
    2016-08-31
    Author
    Roth, Alexandra K.
    Publisher
    University of Kansas
    Format
    57 pages
    Type
    Dissertation
    Degree Level
    Ph.D.
    Discipline
    Psychology
    Rights
    Copyright held by the author.
    Metadata
    Show full item record
    Abstract
    Very little research has been conducted with older adult samples of individuals with multiple sclerosis (MS). In particular, it is not clear whether the cognitive profile of older adult MS patients follows the same patterns observed in younger MS patients. At the level of an individual patient, possible etiologies for changes in cognition include worsening MS, normal consequences of aging, the development of a comorbid condition, or an interaction of these possibilities. This study compared the performance of MS (n = 64), amnestic mild cognitive impairment (aMCI; n = 58), and healthy control (n = 70) samples over the age of 60 on a neuropsychological testing battery. Older adult MS patients consistently performed better than aMCI patients and worse than controls. However, secondary progressive MS patients did not significantly differ from aMCI patients on any cognitive measure. Criteria for cognitive impairment were met by 20% of the MS sample. MS patients were most frequently impaired on tasks of processing speed and memory. Significant predictors of cognitive impairment were physical disability and disease duration. Overall, the cognitive profile of older adult MS patients is largely consistent with that of younger MS patients. However, differences in impairment between secondary progressive and primary progressive patients were not as distinct as previously reported in the literature. Additionally, disease duration was more strongly associated with cognitive impairment than previously thought.
    URI
    http://hdl.handle.net/1808/26023
    Collections
    • Psychology Dissertations and Theses [466]
    • Dissertations [4320]

    Items in KU ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.


    We want to hear from you! Please share your stories about how Open Access to this item benefits YOU.


    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

    Browse

    All of KU ScholarWorksCommunities & CollectionsThis Collection

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

    The University of Kansas
      Contact KU ScholarWorks
    Lawrence, KS | Maps
     
    • Academics
    • Admission
    • Alumni
    • Athletics
    • Campuses
    • Giving
    • Jobs

    The University of Kansas prohibits discrimination on the basis of race, color, ethnicity, religion, sex, national origin, age, ancestry, disability, status as a veteran, sexual orientation, marital status, parental status, gender identity, gender expression and genetic information in the University’s programs and activities. The following person has been designated to handle inquiries regarding the non-discrimination policies: Director of the Office of Institutional Opportunity and Access, IOA@ku.edu, 1246 W. Campus Road, Room 153A, Lawrence, KS, 66045, (785)864-6414, 711 TTY.

     Contact KU
    Lawrence, KS | Maps