The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology
dc.contributor.author | Huang, Jingshan | |
dc.contributor.author | Eilbeck, Karen | |
dc.contributor.author | Smith, Barry | |
dc.contributor.author | Blake, Judith A. | |
dc.contributor.author | Dou, Dejing | |
dc.contributor.author | Huang, Weili | |
dc.contributor.author | Natale, Darren A. | |
dc.contributor.author | Ruttenberg, Alan | |
dc.contributor.author | Huan, Jun | |
dc.contributor.author | Zimmermann, Michael T. | |
dc.contributor.author | Jiang, Guoqian | |
dc.contributor.author | Lin, Yu | |
dc.contributor.author | Wu, Bin | |
dc.contributor.author | Strachan, Harrison J. | |
dc.contributor.author | He, Yongqun | |
dc.contributor.author | Zhang, Shaojie | |
dc.contributor.author | Wang, Xiaowei | |
dc.contributor.author | Liu, Zixing | |
dc.contributor.author | Borchert, Glen M. | |
dc.contributor.author | Tan, Ming | |
dc.date.accessioned | 2017-12-06T21:32:43Z | |
dc.date.available | 2017-12-06T21:32:43Z | |
dc.date.issued | 2016-05-04 | |
dc.identifier.citation | Huang, J., Eilbeck, K., Smith, B., Blake, J. A., Dou, D., Huang, W., ... & Jiang, G. (2016). The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology. Journal of biomedical semantics, 7(1), 24. | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/25597 | |
dc.description.abstract | In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users, accessible at: http://purl.obolibrary.org/obo/ncro.owl. | en_US |
dc.publisher | BioMed Central | en_US |
dc.rights | © 2016 Huang et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Non-coding RNA | en_US |
dc.subject | Biomedical ontology | en_US |
dc.subject | Domain ontology | en_US |
dc.subject | Reference ontology | en_US |
dc.subject | Ontology development | en_US |
dc.subject | Data annotation | en_US |
dc.title | The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Huan, Jun | |
kusw.kudepartment | Electrical Engineering and Computer Science | en_US |
dc.identifier.doi | 10.1186/s13326-016-0066-0 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess | en_US |
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(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.