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dc.contributor.authorSzczepanik, Joanna E.
dc.contributor.authorFurey, Maura L.
dc.contributor.authorNugent, Allison C.
dc.contributor.authorHenter, Ioline D.
dc.contributor.authorZarate, Carlos A., Jr.
dc.contributor.authorLejuez, Carl W.
dc.date.accessioned2017-11-08T20:18:08Z
dc.date.available2017-11-08T20:18:08Z
dc.date.issued2017-10-09
dc.identifier.citationSzczepanik, J. E., Furey, M. L., Nugent, A. C., Henter, I. D., Zarate Jr, C. A., & Lejuez, C. W. (2017). Altered interaction with environmental reinforcers in major depressive disorder: Relationship to anhedonia. Behaviour research and therapy, 97, 170-177.en_US
dc.identifier.urihttp://hdl.handle.net/1808/25292
dc.description.abstractAnhedonia—defined as loss of interest or pleasure—is one of two core symptoms of major depressive disorder (MDD). Anhedonia may involve decreased enjoyment of potentially rewarding activities and decreased motivation to engage in such activities. Increased engagement with reinforcers—activities with the potential to be positive experiences—is a frequent target of cognitive-behavioral therapies. Nevertheless, how environmental reinforcers are perceived, and how decisions to approach or avoid them are made by individuals with MDD, is largely unknown. We developed an experimental Behavioral Approach Motivation Paradigm to study how activities are evaluated and approached in MDD. Twenty-one MDD participants and 23 healthy controls performed an experimental task that rated activity words for their hedonic value, then engaged in an approach-avoidance joystick task with each individual’s unique set of ‘liked’ and ‘disliked’ activity words. A negative correlation was observed between anhedonia and the number of ‘liked’ activities across participants. No significant difference between approach and avoidance behavior was found in direct comparisons between healthy controls and MDD participants; however, weaker avoidance and greater approach toward ‘disliked’ activities was found in MDD participants. This suggests negative bias in selecting environmental opportunities, potentially further compromising access to hedonic experiences in MDD.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectAnhedoniaen_US
dc.subjectApproachen_US
dc.subjectAvoidanceen_US
dc.subjectBehavioral activationen_US
dc.subjectMajor depressive disorderen_US
dc.subjectReinforcementen_US
dc.titleAltered interaction with environmental reinforcers in major depressive disorder: Relationship to anhedoniaen_US
dc.typeArticleen_US
kusw.kuauthorLejuez, Carl W.
kusw.kudepartmentPsychologyen_US
dc.identifier.doi10.1016/j.brat.2017.08.003en_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
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dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.