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Validity of anthropometric equations to estimate infant fat mass at birth and in early infancy

Cauble, Jennifer S.
Dewi, Mira
Hull, Holly R.
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Abstract
Background: In newborns and children, body fat estimation equations are often used at different ages than the age used to develop the equations. Limited validation studies exist for newborn body fat estimation equations at birth or later in infancy. The study purpose was to validate 4 newborn fat mass (FM) estimation equations in comparison to FM measured by air displacement plethysmography (ADP; the Pea Pod) at birth and 3 months. Methods: Ninety-five newborns (1–3 days) had their body composition measured by ADP and anthropometrics assessed by skinfolds. Sixty-three infants had repeat measures taken (3 months). FM measured by ADP was compared to FM from the skinfold estimation equations (Deierlein, Catalano, Lingwood, and Aris). Paired t-tests assessed mean differences, linear regression assessed accuracy, precision was assessed by R2 and standard error of the estimate (SEE), and bias was assessed by Bland-Altman plots. Results: At birth, FM measured by ADP differed from FM estimated by Deierlein, Lingwood and Aris equations, but did not differ from the Catalano equation. At 3 months, FM measured by ADP was different from all equations. At both time points, poor precision and accuracy was detected. Bias was detected in most all equations. Conclusions: Poor agreement, precision, and accuracy were found between prediction equations and the criterion at birth and 3 months.
Description
A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.
Date
2017-03
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BioMed Central
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Keywords
Prediction equations, Infant, Fat mass, Anthropometrics, ADP, Skinfolds
Citation
Cauble, J. S., Dewi, M., & Hull, H. R. (2017). Validity of anthropometric equations to estimate infant fat mass at birth and in early infancy. BMC Pediatrics, 17, 88. http://doi.org/10.1186/s12887-017-0844-6
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