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dc.contributor.authorColombo, John
dc.contributor.authorCarlson, Susan E.
dc.contributor.authorCheatham, Carol L.
dc.contributor.authorFitzgerald-Gustafson, Kathleen M.
dc.contributor.authorKepler, Amy
dc.contributor.authorDoty, Tasha
dc.date.accessioned2017-06-27T20:28:53Z
dc.date.available2017-06-27T20:28:53Z
dc.date.issued2011-10
dc.identifier.citationColombo, J., Carlson, S. E., Cheatham, C. L., Fitzgerald-Gustafson, K. M., Kepler, A., & Doty, T. (2011). Long Chain Polyunsaturated Fatty Acid Supplementation in Infancy Reduces Heart Rate and Positively Affects Distribution of Attention. Pediatric Research, 70(4), 406–410. http://doi.org/10.1203/PDR.0b013e31822a59f5en_US
dc.identifier.urihttp://hdl.handle.net/1808/24670
dc.description.abstractA double-blind, randomized, controlled, parallel-group prospective trial was conducted to determine whether a dose-response existed for four different levels of docosahexaenoic acid (DHA) supplementation on the cognitive performance of infants. A total of 122 term infants were fed one of four different formulas varying in their DHA composition (0.00%, 0.32%, 0.64% and 0.96% of total fatty acids as DHA) from birth to 12 months. The three DHA-supplemented formulas also contained 0.64% of total fatty acids as arachidonic acid (ARA, 20:4n-6). Infants were tested at 4, 6, and 9 months of age on a visual habituation protocol that yielded both behavioral and psychophysiological indices of attention. Infants in all DHA+ARA-supplemented conditions had lower heart rates than those in the unsupplemented condition; there was no dose-response for this effect. The distribution of time that infants spent in different phases of attention (a cognitive index derived from the convergence of behavioral and cardiac responses) varied as a function of dosage. Infants supplemented at the two lower DHA doses spent proportionately more time engaged in active stimulus processing than infants fed the unsupplemented formula, while infants fed the highest dose were intermediate and did not differ from any other group.en_US
dc.publisherNature Publishing Groupen_US
dc.titleLong Chain Polyunsaturated Fatty Acid Supplementation in Infancy Reduces Heart Rate and Positively Affects Distribution of Attentionen_US
dc.typeArticleen_US
kusw.kuauthorColombo, John
kusw.kudepartmentPsychologyen_US
dc.identifier.doi10.1203/PDR.0b013e31822a59f5en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-8841-0105
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC3172991en_US
dc.rights.accessrightsopenAccess


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