dc.contributor.author | Torre, Peter, III | |
dc.contributor.author | Zeldow, Bret | |
dc.contributor.author | Hoffman, Howard J. | |
dc.contributor.author | Buchanan, Ashley L. | |
dc.contributor.author | Siberry, George K. | |
dc.contributor.author | Rice, Mabel L. | |
dc.contributor.author | Sirois, Patricia A. | |
dc.contributor.author | Williams, Paige L. | |
dc.date.accessioned | 2017-06-27T20:22:32Z | |
dc.date.available | 2017-06-27T20:22:32Z | |
dc.date.issued | 2012-08 | |
dc.identifier.citation | Torre, P., Zeldow, B., Hoffman, H. J., Buchanan, A., Siberry, G. K., Rice, M., … for the Pediatric HIV/AIDS Cohort Study. (2012). Hearing Loss in Perinatally Human Immunodeficiency Virus-Infected and Human Immunodeficiency Virus -Exposed but Uninfected Children and Adolescents. The Pediatric Infectious Disease Journal, 31(8), 835–841. http://doi.org/10.1097/INF.0b013e31825b9524 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/24669 | |
dc.description | This is not the published version. | en_US |
dc.description.abstract | Background Little is known about hearing loss in children with HIV infection (HIV+). We examined the prevalence of hearing loss in perinatally HIV+ and HIV-exposed but uninfected (HEU) children, compared these to the percentage with hearing loss in the general population, and evaluated possible risk factors for hearing loss in HIV+ and HEU children. Methods Audiometric examinations were completed in children who met any pre-specified criteria for possible hearing loss. The hearing examination consisted of a tympanogram in each ear and pure-tone air-conduction threshold testing from 500 through 4000 Hz. Hearing loss was defined as the pure-tone average over these frequencies ≥20 dB hearing level (HL). The associations of demographic, parent/caregiver, HIV disease, and HIV treatment with hearing loss were evaluated with univariate and multivarible logistic regression models. Results Hearing testing was completed in 231 children (145 HIV+ and 86 HEU). Hearing loss occurred in 20.0% of HIV+ children and 10.5% of HEU children. After adjusting for caregiver education level, HIV infection was associated with increased odds of hearing loss [adjusted odds ratio (aOR)=2.13, 95% confidence interval (CI): 0.95–4.76, p=0.07]. Among HIV+ children, those with a CDC Class C diagnosis had over twice the odds of hearing loss (aOR=2.47, 95% CI: 1.04–5.87, p=0.04). The prevalence of hearing loss was higher in both HIV+ and HEU children compared with NHANES III children. Conclusions Hearing loss was more common in both HIV+ and HEU children than in healthy children. More advanced HIV illness increased the risk of hearing loss in HIV+ children. | en_US |
dc.publisher | Lippincott, Williams & Wilkins | en_US |
dc.title | Hearing Loss in Perinatally Human Immunodeficiency Virus- Infected and Human Immunodeficiency Virus -Exposed but Uninfected Children and Adolescents | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Rice, Mabel L. | |
kusw.kudepartment | Speech-Language-Hearing | en_US |
dc.identifier.doi | 10.1097/INF.0b013e31825b9524 | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC3410657 | en_US |
dc.rights.accessrights | openAccess | |