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Spatially and temporally varying selection on intra-population QTL for a life history tradeoff in Mimulus guttatus
dc.contributor.author | Mojica, Julius Penalba | |
dc.contributor.author | Lee, Young Wha | |
dc.contributor.author | Willis, John H. | |
dc.contributor.author | Kelly, John K. | |
dc.date.accessioned | 2017-06-22T21:43:52Z | |
dc.date.available | 2017-06-22T21:43:52Z | |
dc.date.issued | 2012-08 | |
dc.identifier.citation | MOJICA, J. P., LEE, Y. W., WILLIS, J. H. and KELLY, J. K. (2012), Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. Molecular Ecology, 21: 3718–3728. doi:10.1111/j.1365-294X.2012.05662.x | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/24588 | |
dc.description | This is the peer reviewed version of the following article: MOJICA, J. P., LEE, Y. W., WILLIS, J. H. and KELLY, J. K. (2012), Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. Molecular Ecology, 21: 3718–3728. doi:10.1111/j.1365-294X.2012.05662.x, which has been published in final form at http://doi.org/10.1111/j.1365-294X.2012.05662.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. | en_US |
dc.description.abstract | Why do populations remain genetically variable despite strong continuous natural selection? Mutation reconstitutes variation eliminated by selection and genetic drift, but theoretical and experimental studies each suggest that mutation-selection balance insufficient to explain extant genetic variation in most complex traits. The alternative hypothesis of balancing selection, wherein selection maintains genetic variation, is an aggregate of multiple mechanisms (spatial and temporal heterogeneity in selection, frequency-dependent selection, antagonistic pleiotropy, etc.). Most of these mechanisms have been demonstrated for Mendelian traits, but there is little comparable data for loci affecting quantitative characters. Here, we report a three-year field study of selection on intra-population Quantitative Trait Loci (QTL) of flower size, a highly polygenic trait of Mimulus guttatus. The QTL exhibit antagonistic pleiotropy: alleles that increase flower size reduce viability but increase fecundity. The magnitude and direction of selection fluctuates yearly and on a spatial scale of meters. This study provides direct evidence of balancing selection mechanisms on QTL of an ecologically relevant trait. | en_US |
dc.publisher | Wiley | en_US |
dc.subject | Balancing selection | en_US |
dc.subject | Mimulus guttatus | en_US |
dc.subject | Pleiotropy | en_US |
dc.subject | QTL | en_US |
dc.title | Spatially and temporally varying selection on intra-population QTL for a life history tradeoff in Mimulus guttatus | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Mojica, Julius P. | |
kusw.kuauthor | Kelly, John K. | |
kusw.kudepartment | Ecology and Evolutionary Biology | en_US |
dc.identifier.doi | 10.1111/j.1365-294X.2012.05662.x | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC3883364 | en_US |
dc.rights.accessrights | openAccess |