Anolis sex chromosomes are derived from a single ancestral pair
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Issue Date
2014-04Author
Gamble, Tony
Geneva, Anthony J.
Glor, Richard E.
Zarkower, David
Publisher
Wiley
Type
Article
Article Version
Scholarly/refereed, author accepted manuscript
Metadata
Show full item recordAbstract
To explain the frequency and distribution of heteromorphic sex chromosomes in the lizard genus Anolis we compared the relative roles of sex chromosome conservation vs. turnover of sex determining mechanisms. We used model based comparative methods to reconstruct karyotype evolution and the presence of heteromorphic sex chromosomes onto a newly generated Anolis phylogeny. We found that heteromorphic sex chromosomes evolved multiple times in the genus. Fluorescent in situ hybridization (FISH) of repetitive DNA showed variable rates of Y chromosome degeneration among Anolis species and identified previously undetected, homomorphic sex chromosomes in two species. We confirmed homology of sex chromosomes in the genus by performing FISH of an X-linked BAC and qPCR of X-linked genes in multiple Anolis species sampled across the phylogeny. Taken together, these results are consistent with long-term conservation of sex chromosomes in the group. Our results pave the way to address additional questions related to Anolis sex chromosome evolution and describe a conceptual framework that can be used to evaluate the origins and evolution of heteromorphic sex chromosomes in other clades.
Description
This is the peer reviewed version of the following article: Gamble, T., Geneva, A. J., Glor, R. E., & Zarkower, D. (2014). Anolis sex chromosomes are derived from a single ancestral pair. Evolution; International Journal of Organic Evolution, 68(4), 1027–1041. http://doi.org/10.1111/evo.12328, which has been published in final form at http://doi.org/10.1111/evo.12328. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
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Citation
Gamble, T., Geneva, A. J., Glor, R. E., & Zarkower, D. (2014). Anolis sex chromosomes are derived from a single ancestral pair. Evolution; International Journal of Organic Evolution, 68(4), 1027–1041. http://doi.org/10.1111/evo.12328
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