Show simple item record

Detection of cocaine induced rat brain activation by photoacoustic tomography

dc.contributor.authorJo, Janggun
dc.contributor.authorYang, Xinmai
dc.date.accessioned2017-05-16T14:46:05Z
dc.date.available2017-05-16T14:46:05Z
dc.date.issued2011-02-15
dc.identifier.citationJo, J., & Yang, X. (2011). Detection of cocaine induced rat brain activation by photoacoustic tomography. Journal of Neuroscience Methods, 195(2), 232–235. http://doi.org/10.1016/j.jneumeth.2010.12.006en_US
dc.identifier.urihttp://hdl.handle.net/1808/24214
dc.description.abstractPhotoacoustic tomography (PAT) was used to detect the progressive changes on the cerebral cortex of Sprague Dawley rats after the administration of cocaine hydrochloride. Different concentrations (0, 2.5, and 5.0 mg per kg body) of cocaine hydrochloride in saline solution were injected into Sprague Dawley rats through tail veins. Cerebral cortex images of the animals were continuously acquired by PAT. For continuous observation, PAT system used multi-transducers to reduce the scanning time and maintain a good signal-to-noise ratio (SNR). The obtained photoacoustic images were compared with each other and confirmed that changes in blood volume were induced by cocaine hydrochloride injection. The results demonstrate that PAT may be used to detect the effects of drug abuse-induced brain activation.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectPhotoacoustic tomographyen_US
dc.subjectImagingen_US
dc.subjectCocaineen_US
dc.subjectDrug abuseen_US
dc.subjectBrainen_US
dc.subjectCerebral cortexen_US
dc.titleDetection of cocaine induced rat brain activation by photoacoustic tomographyen_US
dc.typeArticleen_US
kusw.kuauthorJo, Janggun
kusw.kuauthorYang, Xinmai
kusw.kudepartmentMechanical Engineeringen_US
dc.identifier.doi10.1016/j.jneumeth.2010.12.006en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC3026864en_US
dc.rights.accessrightsopenAccess


Files in this item

Thumbnail
Name:
Jo_2011.pdf
Size:
98.07Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.