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dc.contributor.authorBury, Scott D.
dc.contributor.authorPlautz, Erik J.
dc.contributor.authorLiu, Wen
dc.contributor.authorQuaney, Barbara M.
dc.contributor.authorLuchies, Carl W.
dc.contributor.authorMaletsky, Rebecca A.
dc.contributor.authorNudo, Randolph J.
dc.date.accessioned2017-05-16T14:33:44Z
dc.date.available2017-05-16T14:33:44Z
dc.date.issued2009-05-15
dc.identifier.citationBury, S. D., Plautz, E. J., Liu, W., Quaney, B. M., Luchies, C. W., Maletsky, R. A., & Nudo, R. J. (2009). A novel device to measure power grip forces in squirrel monkeys. Journal of Neuroscience Methods, 179(2), 264–270. http://doi.org/10.1016/j.jneumeth.2009.02.003en_US
dc.identifier.urihttp://hdl.handle.net/1808/24212
dc.description.abstractUnderstanding the neural bases for grip force behaviors in both normal and neurologically impaired animals is imperative prior to improving treatments and therapeutic approaches. The present paper describes a novel device for the assessment of power grip forces in squirrel monkeys. The control of grasping and object manipulation represents a vital aspect of daily living by allowing the performance of a wide variety of complex hand movements. However, following neurological injury such as stroke, these grasping behaviors are often severely affected, resulting in persistent impairments in strength, grip force modulation and kinematic hand control. While there is a significant clinical focus on rehabilitative strategies to address these issues, there exists the need for translational animal models. In the study presented here, we describe a simple grip force device designed for use in nonhuman primates, which provides detailed quantitative information regarding distal grip force dynamics. Adult squirrel monkeys were trained to exceed a specific grip force threshold, which was rewarded with a food pellet. One of these subjects then received an infarct of the M1 hand representation area. Results suggest that the device provides detailed and reliable information on grip behaviors in healthy monkeys and can detect deficits in grip dynamics in monkeys with cortical lesions (significantly longer release times). Understanding the physiological and neuroanatomical aspects of grasping function following neurological injury may lead to more effective rehabilitative interventions.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectGrip forceen_US
dc.subjectPower gripen_US
dc.subjectMonkeyen_US
dc.subjectStrokeen_US
dc.subjectHanden_US
dc.subjectPrimateen_US
dc.titleA novel device to measure power grip forces in squirrel monkeysen_US
dc.typeArticleen_US
kusw.kuauthorLuchies, Carl W.
kusw.kudepartmentMechanical Engineeringen_US
dc.identifier.doi10.1016/j.jneumeth.2009.02.003en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC2700290en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.