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Chlorinated Withanolides from Withania somnifera

dc.contributor.authorTong, Xiaoqin
dc.contributor.authorZhang, Huaping
dc.contributor.authorTimmermann, Barbara N.
dc.date.accessioned2017-05-08T20:32:16Z
dc.date.available2017-05-08T20:32:16Z
dc.date.issued2011-12
dc.identifier.citationTong, Xiaoqin, Huaping Zhang, and Barbara N. Timmermann. “Chlorinated Withanolides from Withania Somnifera.” Phytochemistry letters 4.4 (2011): 411–414.en_US
dc.identifier.urihttp://hdl.handle.net/1808/24028
dc.description.abstractA chlorinated withanolide, 6α-chloro-5β,17α-dihydroxywithaferin A (1), and nine known withanolides, 6α-chloro-5β-hydroxywithaferin A (2), (22R)-5β-formyl-6β,27-dihydroxy-1-oxo-4-norwith-24-enolide, withaferin A, 2,3-dihydrowithaferin A, 3-methoxy-2,3-dihydrowithaferin A, 2,3-didehydrosomnifericin, withanone, withanoside IV and withanoside X, were isolated from Withania somnifera (Solanaceae). All structures were elucidated on the basis of spectroscopic methods (IR, HRESIMS, 1D/2D NMR). X-ray crystallography confirmed the absolute configuration of 1.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subjectChlorinated withanolideen_US
dc.subjectWithania somniferaen_US
dc.subjectSolanaceaeen_US
dc.subjectNMRen_US
dc.subjectCrystal structureen_US
dc.titleChlorinated Withanolides from Withania somniferaen_US
dc.typeArticleen_US
kusw.kuauthorTimmermann, Barbara N.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1016/j.phytol.2011.04.016en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC3223914en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.