Life Span Institute: Recent submissions
Now showing items 41-60 of 248
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Postural control processes during standing and step initiation in autism spectrum disorder
(BMC, 2020-01-06)Background Individuals with autism spectrum disorder (ASD) show a reduced ability to maintain postural stability, though motor control mechanisms contributing to these issues and the extent to which they are associated ... -
Adapting the Diabetes Prevention Program for low and middle-income countries: protocol for a cluster randomised trial to evaluate ‘Lifestyle Africa’
(BMJ Publishing Group, 2019-11-11)Introduction Low and middle-income countries like South Africa are experiencing major increases in burden of non-communicable diseases such as diabetes and cardiovascular conditions. However, evidence-based interventions ... -
Precision Sensorimotor Control in Aging FMR1 Gene Premutation Carriers
(Frontiers Media, 2019-10-02)Background: Individuals with premutation alleles of the FMR1 gene are at risk of developing fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative condition affecting sensorimotor function. Information ... -
Assessing whether early attention of very preterm infants can be improved by an omega-3 long-chain polyunsaturated fatty acid intervention: a follow-up of a randomised controlled tria
(BMJ, 2018-05-26)Introduction Docosahexaenoic acid (DHA) accumulates in the frontal lobes (responsible for higher-order cognitive skills) of the fetal brain during the last trimester of pregnancy. Infants born preterm miss some of this ... -
Maternal Vitamin D Status and Infant Infection
(MDPI, 2018-01-23)Maternal vitamin D status during pregnancy may modulate fetal immune system development and infant susceptibility to infections. Vitamin D deficiency is common during pregnancy, particularly among African American (AA) ... -
Hyper-Palatable Foods: Development of a Quantitative Definition and Application to the US Food System Database
(Wiley, 2019-11-05)Objective: Extensive research has focused on hyper-palatable foods (HPF); however, HPF are defined using descriptive terms (e.g., fast foods, sweets), which are not standardized and lack specificity. The study purpose was ... -
Precision Sensorimotor Control in Aging FMR1 Gene Premutation Carriers
(Frontiers Media, 2019-10-02)Background: Individuals with premutation alleles of the FMR1 gene are at risk of developing fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative condition affecting sensorimotor function. Information ... -
Cortical and subcortical alterations associated with precision visuomotor behavior in individuals with autism spectrum disorder
(American Physiological Society, 2019-09-23)In addition to core deficits in social-communication abilities and repetitive behaviors and interests, many 2 patients with autism spectrum disorder (ASD) experience developmental comorbidities, including 3 sensorimotor ... -
Parents’ Perspectives on the Theoretical Domains Framework Elements Needed in a Pediatric Health Behavior App: A Crowdsourced Social Validity Study
(JMIR Publications, 2018-12-21)Background: Most pediatric studies do not include parent stakeholders in the design of the intervention itself and many pediatric mobile health (mHealth) interventions are not meaningfully disseminated after the trial ... -
Systematic Replication of the Effects of a Supplementary, Technology-Assisted, Storybook Intervention for Preschool Children with Weak Vocabulary and Comprehension Skills
(University of Chicago Press, 2016-06)In 2013, Spencer, Goldstein, Sherman, et al. reported the promising effects of a supplemental, technology-assisted, storybook intervention (Tier 2) containing embedded instruction targeting the oral language learning of ... -
Alterations in the functional neural circuitry supporting flexible choice behavior in autism spectrum disorders
(Nature Publishing Group, 2016-10-11)Restricted and repetitive behaviors, and a pronounced preference for behavioral and environmental consistency, are distinctive characteristics of autism spectrum disorder (ASD). Alterations in frontostriatal circuitry that ... -
Reduced habituation of auditory evoked potentials indicate cortical hyper-excitability in Fragile X Syndrome
(Nature Publishing Group, 2016-04-19)Sensory hypersensitivities are common, clinically distressing features of Fragile X Syndrome (FXS). Preclinical evidence suggests this abnormality may result from synaptic hyper-excitability in sensory systems. This model ... -
Postural orientation and equilibrium processes associated with increased postural sway in autism spectrum disorder (ASD)
(BioMed Central, 2016-11-25)Background: Increased postural sway has been repeatedly documented in children with autism spectrum disorder (ASD). Characterizing the control processes underlying this deficit, including postural orientation and equilibrium, ... -
Energy Expenditure and Physical Activity in Prader–Willi Syndrome Comparison With Obese Subjects
(Wiley, 2007-03-01)Prader–Willi syndrome (PWS) is a complex neurodevelopmental disorder characterized by hypotonia, suck and feeding difficulties, hypogonadism, small hands and feet, developmental delay, hyperphagia and early childhood obesity ... -
Comparing Audio and Video Data for Rating Communication
(SAGE Publications, 2013-09)Video recording has become increasingly popular in nursing research, adding rich nonverbal, contextual, and behavioral information. However, benefits of video over audio data have not been well established. We compared ... -
Weight Loss Can Lead to Resolution of Gastroesophageal Reflux Disease Symptoms: A Prospective Intervention Trial
(Wiley, 2013-02)OBJECTIVE Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight ... -
Equivalent weight loss for weight management programs delivered by phone and clinic
(Wiley, 2013-10)OBJECTIVE Face-to-face weight management is costly and presents barriers for individuals seeking treatment; thus, alternate delivery systems are needed. The objective of this study was to compare weight management delivered ... -
Aerobic exercise alone results in clinically significant weight loss for men and women: Midwest Exercise Trial-2
(Wiley, 2013-03)Exercise is recommended by public health agencies for weight management; however, the role of exercise is generally considered secondary to energy restriction. Few studies exist that have verified completion of exercise, ... -
Infant Visual Habituation
(Elsevier, 2009-09)The use of visual habituation in the study of infant cognition and learning is reviewed. This article traces the history of the technique, underlying theory, and procedural variation in its measurement. In addition, we ... -
Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington’s disease
(Elsevier, 2010-01)Altered neuronal activity in the striatum appears to be a key component of Huntington’s disease (HD), a fatal, neurodegenerative condition. To assess this hypothesis in freely behaving transgenic rats that model HD (tgHDs), ...