ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine
| dc.contributor.author | Niphakis, Micah James | |
| dc.contributor.author | Georg, Gunda I. | |
| dc.date.accessioned | 2017-04-13T17:48:48Z | |
| dc.date.available | 2017-04-13T17:48:48Z | |
| dc.date.issued | 2010-09-03 | |
| dc.identifier.citation | Niphakis, M. J., & Georg, G. I. (2010). Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine. The Journal of Organic Chemistry, 75(17), 6019–6022. http://doi.org/10.1021/jo101051w | en_US |
| dc.identifier.uri | http://hdl.handle.net/1808/23697 | |
| dc.description.abstract | This paper presents the first application of two recently developed reactions to natural product synthesis. The first method involves a 6-endo-trig cyclization to prepare a versatile chiral enaminone building block. The second is a direct C–H arylation reaction. As a showcase for the utility of these methods, (+)-antofine and (+)-ipalbidine were synthesized in only 8 steps and 24–26% overall yields. | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.rights | This document is the Accepted Manuscript version of a Published Work that appeared in final form in the Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jo101051w. | en_US |
| dc.title | Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine | en_US |
| dc.type | Article | en_US |
| kusw.kuauthor | Niphakis, Micah J. | |
| kusw.kuauthor | Georg, Gunda | |
| kusw.kudepartment | Medicinal Chemistry | en_US |
| dc.identifier.doi | 10.1021/jo101051w | en_US |
| kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
| kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
| dc.rights.accessrights | openAccess |
