| dc.contributor.author | Niphakis, Micah James | |
| dc.contributor.author | Georg, Gunda I. | |
| dc.date.accessioned | 2017-04-13T17:48:48Z | |
| dc.date.available | 2017-04-13T17:48:48Z | |
| dc.date.issued | 2010-09-03 | |
| dc.identifier.citation | Niphakis, M. J., & Georg, G. I. (2010). Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine. The Journal of Organic Chemistry, 75(17), 6019–6022. http://doi.org/10.1021/jo101051w | en_US |
| dc.identifier.uri | http://hdl.handle.net/1808/23697 | |
| dc.description.abstract | This paper presents the first application of two recently developed reactions to natural product synthesis. The first method involves a 6-endo-trig cyclization to prepare a versatile chiral enaminone building block. The second is a direct C–H arylation reaction. As a showcase for the utility of these methods, (+)-antofine and (+)-ipalbidine were synthesized in only 8 steps and 24–26% overall yields. | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.rights | This document is the Accepted Manuscript version of a Published Work that appeared in final form in the Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jo101051w. | en_US |
| dc.title | Total Syntheses of Arylindolizidine Alkaloids (+)-Ipalbidine and (+)-Antofine | en_US |
| dc.type | Article | en_US |
| kusw.kuauthor | Niphakis, Micah J. | |
| kusw.kuauthor | Georg, Gunda | |
| kusw.kudepartment | Medicinal Chemistry | en_US |
| dc.identifier.doi | 10.1021/jo101051w | en_US |
| kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
| kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
| dc.rights.accessrights | openAccess | |
