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Regioselective C5-alkylation and C5-methylcarbamate formation of 2,3-dihydro-4-pyridones and C3-alkylation and C3-methylcarbamate formation of 4-(pyrrolidin-1-yl)furan-2(5H)-one
dc.contributor.author | Gu, Xingxian | |
dc.contributor.author | Georg, Gunda I. | |
dc.date.accessioned | 2017-04-10T20:48:45Z | |
dc.date.available | 2017-04-10T20:48:45Z | |
dc.date.issued | 2015-10-21 | |
dc.identifier.citation | Gu, Xingxian, and Gunda I. Georg. “Regioselective C5-Alkylation and C5-Methylcarbamate Formation of 2,3-Dihydro-4-Pyridones and C3-Alkylation and C3-Methylcarbamate Formation of 4-(pyrrolidin-1-Yl)furan-2(5H)-One.” Tetrahedron letters 56.43 (2015): 5874–5877. | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/23622 | |
dc.description.abstract | Reactions of N-alkyl-2,3-dihydro-4-pyridones and 4-(pyrrolidin-1-yl)furan-2(5H)-one with aldehydes and triethylsilane in a one-flask procedure provided C5 and C3 alkylated derivatives, respectively. Mannich-type reactions with formaldehyde and carbamates in the presence of lithium perchlorate furnished C5/C3 methylcarbamates. | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | |
dc.subject | 2, 3-dihydro-4pyridones | en_US |
dc.subject | 4-(pyrrolidin-1-yl) furan-2(5H)-one | en_US |
dc.subject | Regioselective alkylation | en_US |
dc.subject | Mannich reaction | en_US |
dc.title | Regioselective C5-alkylation and C5-methylcarbamate formation of 2,3-dihydro-4-pyridones and C3-alkylation and C3-methylcarbamate formation of 4-(pyrrolidin-1-yl)furan-2(5H)-one | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Georg, Gunda I. | |
kusw.kudepartment | Medicinal Chemistry | en_US |
dc.identifier.doi | 10.1016/j.tetlet.2015.09.004 | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess |
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