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Regioselective C5-alkylation and C5-methylcarbamate formation of 2,3-dihydro-4-pyridones and C3-alkylation and C3-methylcarbamate formation of 4-(pyrrolidin-1-yl)furan-2(5H)-one

dc.contributor.authorGu, Xingxian
dc.contributor.authorGeorg, Gunda I.
dc.date.accessioned2017-04-10T20:48:45Z
dc.date.available2017-04-10T20:48:45Z
dc.date.issued2015-10-21
dc.identifier.citationGu, Xingxian, and Gunda I. Georg. “Regioselective C5-Alkylation and C5-Methylcarbamate Formation of 2,3-Dihydro-4-Pyridones and C3-Alkylation and C3-Methylcarbamate Formation of 4-(pyrrolidin-1-Yl)furan-2(5H)-One.” Tetrahedron letters 56.43 (2015): 5874–5877.en_US
dc.identifier.urihttp://hdl.handle.net/1808/23622
dc.description.abstractReactions of N-alkyl-2,3-dihydro-4-pyridones and 4-(pyrrolidin-1-yl)furan-2(5H)-one with aldehydes and triethylsilane in a one-flask procedure provided C5 and C3 alkylated derivatives, respectively. Mannich-type reactions with formaldehyde and carbamates in the presence of lithium perchlorate furnished C5/C3 methylcarbamates.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject2, 3-dihydro-4pyridonesen_US
dc.subject4-(pyrrolidin-1-yl) furan-2(5H)-oneen_US
dc.subjectRegioselective alkylationen_US
dc.subjectMannich reactionen_US
dc.titleRegioselective C5-alkylation and C5-methylcarbamate formation of 2,3-dihydro-4-pyridones and C3-alkylation and C3-methylcarbamate formation of 4-(pyrrolidin-1-yl)furan-2(5H)-oneen_US
dc.typeArticleen_US
kusw.kuauthorGeorg, Gunda I.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1016/j.tetlet.2015.09.004en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 3.0 (CC BY-NC-ND 3.0 US), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.