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    Language growth and genetics of specific language impairment

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    rice_language.pdf (916.0Kb)
    Issue Date
    2014-06-01
    Author
    Rice, Mabel L.
    Publisher
    Informa Healthcare
    Type
    Article
    Article Version
    Scholarly/refereed, author accepted manuscript
    Rights
    Copyright Informa Healthcare
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    Abstract
    Behavioural studies of children with specific language impairment (SLI) have reported long term growth outcomes across different dimensions of language. Genetic studies of children with SLI have identified candidate genes and putative associations of gene variants with SLI. The aims of this review are to summarize these two lines of investigation and to highlight the possible role of underlying growth timing mechanisms that influence the trajectory of language outcomes throughout childhood and into adolescence. Behavioural growth trajectories demonstrate that children with SLI have notable strengths in language acquisition, as well as limitations, across different dimensions of language. Language onset appears delayed, although the rate and pattern of change over time is similar to unaffected children. Growth rate decelerates early in adolescence for some dimensions of language. Genetic investigations reveal candidate genes that are known to influence neuronal development, and reveal possible gene interactions along a causal pathway. Epigenetic studies reveal other genetic influences implicated in the cognitive decline associated with aging. This review highlights possible parallels between underlying genetic mechanisms and characteristics of linguistic growth trajectories. The conclusion is that new developmental perspectives are needed to inform language intervention in ways that align nurture with nature.
    URI
    http://hdl.handle.net/1808/23413
    DOI
    https://doi.org/10.3109/17549507.2013.783113
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    • Speech-Language-Hearing Scholarly Works [87]
    Citation
    Rice, Mabel L. "Language Growth and Genetics of Specific Language Impairment." International Journal of Speech-Language Pathology 15.3 (2013): 223-33.

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    KU Libraries
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    785-864-8983

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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