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dc.contributor.authorAmbler, Brett R.
dc.contributor.authorAltman, Ryan A.
dc.date.accessioned2017-03-08T19:49:35Z
dc.date.available2017-03-08T19:49:35Z
dc.date.issued2013-11
dc.identifier.citationAmbler, B. R., & Altman, R. A. (2013). Copper-Catalyzed Decarboxylative Trifluoromethylation of Allylic Bromodifluoroacetates. Organic Letters, 15(21), 10.1021/ol402780k. http://doi.org/10.1021/ol402780ken_US
dc.identifier.urihttp://hdl.handle.net/1808/23363
dc.description.abstractThe development of new synthetic fluorination reactions has important implications in medicinal, agricultural and materials chemistries. Given the prevalence and accessibility of alcohols, methods to convert alcohols to trifluoromethanes are desirable. However, this transformation typically requires four-step processes, specialty chemicals, and/or stoichiometric metals to access the trifluoromethyl-containing product. A two-step copper-catalyzed decarboxylative protocol for converting allylic alcohols to trifluoromethanes is reported. Preliminary mechanistic studies distinguish this reaction from previously reported Cu-mediated reactions.en_US
dc.publisherAmerican Chemical Societyen_US
dc.titleCopper-Catalyzed Decarboxylative Trifluoromethylation of Allylic Bromodifluoroacetatesen_US
dc.typeArticleen_US
kusw.kuauthorAmbler, Brett R.
kusw.kuauthorAltman, Ryan A.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1021/ol402780ken_US
dcterms.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/ol402780k
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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