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Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates

dc.contributor.authorAmbler, Brett R.
dc.contributor.authorPeddi, Santosh
dc.contributor.authorAltman, Ryan A.
dc.date.accessioned2017-01-11T19:42:36Z
dc.date.available2017-01-11T19:42:36Z
dc.date.issued2015-07-15
dc.identifier.citationAltman, Ryan, Brett Ambler, and Santosh Peddi. "Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates." Synthesis 46.14 (2014): 1938-946.en_US
dc.identifier.urihttp://hdl.handle.net/1808/22571
dc.description.abstractThe development of efficient methods for accessing fluorinated functional groups is desirable. Herein, we report a two-step method that utilizes catalytic Cu for the decarboxylative trifluoromethylation of propargyl bromodifluoroacetates. This protocol affords a mixture of propargyl trifluoromethanes and trifluoromethyl allenes.en_US
dc.publisherThieme Publishingen_US
dc.subjectCopperen_US
dc.subjectCatalysisen_US
dc.subjectTrifluoromethylationen_US
dc.subjectDecarboxylationen_US
dc.subjectAlkynesen_US
dc.titleCopper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetatesen_US
dc.typeArticleen_US
kusw.kuauthorAltman, Ryan A.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1055/s-0033-1339128
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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