Role of Zinc in Parkin RING2 E3 Ubiquitin Ligase Ubiquitination
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Rankin, Carolyn A.; Roy, Ambrish; Zhang, Yang; Richter, Mark (Bentham, 2011)Parkin belongs to a class of multiple RING domain proteins designated as RBR (RING, in between RING, RING) proteins. In this review we examine what is known regarding the structure/function relationship of the Parkin ...
Lanfranca, Mirna Perusina; Mostafa, Heba H.; Davido, David J. (MDPI, 2014-05-20)The herpes simplex virus type 1 (HSV-1) encoded E3 ubiquitin ligase, infected cell protein 0 (ICP0), is required for efficient lytic viral replication and regulates the switch between the lytic and latent states of HSV-1. ...
Boutell, Chris; Davido, David J. (Elsevier, 2015-11-15)The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that ...