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dc.contributor.authorTran, Ngoc
dc.contributor.authorBarnoski Serfis, Alexa
dc.contributor.authorOsiecki, John C.
dc.contributor.authorPicking, Wendy Lynn
dc.contributor.authorCoye, Lisette
dc.contributor.authorDavis, Rebecca
dc.contributor.authorPicking, William D.
dc.identifier.citationTran, N., Serfis, A. B., Osiecki, J. C., Picking, W. L., Coye, L., Davis, R., & Picking, W. D. (2000). Interaction of Shigella flexneri IpaC with Model Membranes Correlates with Effects on Cultured Cells. Infection and Immunity, 68(6), 3710–3715.en_US
dc.description.abstractInvasion of enterocytes by Shigella flexneri requires the properly timed release of IpaB and IpaC at the host-pathogen interface; however, only IpaC has been found to possess quantifiable activities in vitro. We demonstrate here that when added to cultured cells, purified IpaC elicits cytoskeletal changes similar to those that occur during Shigella invasion. This IpaC effect may correlate with its ability to interact with model membranes at physiological pH and to promote entry by an ipaC mutant of S. flexneri.en_US
dc.publisherAmerican Society for Microbiologyen_US
dc.rightsCopyright © 2000, American Society for Microbiologyen_US
dc.titleInteraction of Shigella flexneri IpaC with Model Membranes Correlates with Effects on Cultured Cellsen_US
kusw.kuauthorPicking, Wendy Lynn
kusw.kuauthorPicking, William D.
kusw.kudepartmentPharmaceutical Chemistryen_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item does not meet KU Open Access policy criteria.en_US

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