| dc.contributor.author | Tran, Ngoc | |
| dc.contributor.author | Barnoski Serfis, Alexa | |
| dc.contributor.author | Osiecki, John C. | |
| dc.contributor.author | Picking, Wendy Lynn | |
| dc.contributor.author | Coye, Lisette | |
| dc.contributor.author | Davis, Rebecca | |
| dc.contributor.author | Picking, William D. | |
| dc.date.accessioned | 2016-08-15T16:45:54Z | |
| dc.date.available | 2016-08-15T16:45:54Z | |
| dc.date.issued | 2000-06 | |
| dc.identifier.citation | Tran, N., Serfis, A. B., Osiecki, J. C., Picking, W. L., Coye, L., Davis, R., & Picking, W. D. (2000). Interaction of Shigella flexneri IpaC with Model Membranes Correlates with Effects on Cultured Cells. Infection and Immunity, 68(6), 3710–3715. | en_US |
| dc.identifier.uri | http://hdl.handle.net/1808/21322 | |
| dc.description.abstract | Invasion of enterocytes by Shigella flexneri requires the properly timed release of IpaB and IpaC at the host-pathogen interface; however, only IpaC has been found to possess quantifiable activities in vitro. We demonstrate here that when added to cultured cells, purified IpaC elicits cytoskeletal changes similar to those that occur during Shigella invasion. This IpaC effect may correlate with its ability to interact with model membranes at physiological pH and to promote entry by an ipaC mutant of S. flexneri. | en_US |
| dc.publisher | American Society for Microbiology | en_US |
| dc.relation.isversionof | http://iai.asm.org/content/68/6/3710.full?sid=def13237-1346-4e93-9913-9c36b1ec5cb0 | en_US |
| dc.rights | Copyright © 2000, American Society for Microbiology | en_US |
| dc.title | Interaction of Shigella flexneri IpaC with Model Membranes Correlates with Effects on Cultured Cells | en_US |
| dc.type | Article | en_US |
| kusw.kuauthor | Picking, Wendy Lynn | |
| kusw.kuauthor | Picking, William D. | |
| kusw.kudepartment | Pharmaceutical Chemistry | en_US |
| kusw.oanotes | Per SHERPA/RoMEO 8/15/2016: Author's Pre-print: green tick author can archive pre-print (ie pre-refereeing)
Author's Post-print: green tick author can archive post-print (ie final draft post-refereeing)
Publisher's Version/PDF: green tick author can archive publisher's version/PDF
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Publisher's version/PDF may be used on author's personal website or employers website
Recommended that author's post-prints submitted to PubMed or institutional repositories are made available 6 months after publication
Author's pre-print must be updated with citation and DOI upon publication | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0001-7998-0643 | |
| kusw.oaversion | Scholarly/refereed, publisher version | en_US |
| kusw.oapolicy | This item does not meet KU Open Access policy criteria. | en_US |
| dc.rights.accessrights | openAccess | |
