Phylogenetic Analyses of Novel Squamate Adenovirus Sequences in Wild-Caught Anolis Lizards
dc.contributor.author | Ascher, Jill M. | |
dc.contributor.author | Geneva, Anthony J. | |
dc.contributor.author | Ng, Julienne | |
dc.contributor.author | Glor, Richard E. | |
dc.date.accessioned | 2016-06-27T18:12:20Z | |
dc.date.available | 2016-06-27T18:12:20Z | |
dc.date.issued | 2013-04-10 | |
dc.identifier.citation | Article Source: Phylogenetic Analyses of Novel Squamate Adenovirus Sequences in Wild-Caught Anolis Lizards Ascher JM, Geneva AJ, Ng J, Wyatt JD, Glor RE (2013) Phylogenetic Analyses of Novel Squamate Adenovirus Sequences in Wild-Caught Anolis Lizards. PLoS ONE 8(4): e60977. doi: 10.1371/journal.pone.0060977 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/21034 | |
dc.description.abstract | Adenovirus infection has emerged as a serious threat to the health of captive snakes and lizards (i.e., squamates), but we know relatively little about this virus' range of possible hosts, pathogenicity, modes of transmission, and sources from nature. We report the first case of adenovirus infection in the Iguanidae, a diverse family of lizards that is widely-studied and popular in captivity. We report adenovirus infections from two closely-related species of Anolis lizards (anoles) that were recently imported from wild populations in the Dominican Republic to a laboratory colony in the United States. We investigate the evolution of adenoviruses in anoles and other squamates using phylogenetic analyses of adenovirus polymerase gene sequences sampled from Anolis and a range of other vertebrate taxa. These phylogenetic analyses reveal that (1) the sequences detected from each species of Anolis are novel, and (2) adenoviruses are not necessarily host-specific and do not always follow a co-speciation model under which host and virus phylogenies are perfectly concordant. Together with the fact that the Anolis adenovirus sequences reported in our study were detected in animals that became ill and subsequently died shortly after importation while exhibiting clinical signs consistent with acute adenovirus infection, our discoveries suggest the need for renewed attention to biosecurity measures intended to prevent the spread of adenovirus both within and among species of snakes and lizards housed in captivity. | en_US |
dc.publisher | Public Library of Science | en_US |
dc.rights | © 2013 Ascher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | Phylogenetic Analyses of Novel Squamate Adenovirus Sequences in Wild-Caught Anolis Lizards | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Glor, Richard E. | |
kusw.kudepartment | Ecology & Evolutionary Biology | en_US |
dc.identifier.doi | 10.1371/journal.pone.0060977 | |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: © 2013 Ascher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.