Frequency Modulation and Spatiotemporal Stability of the sCPG in Preterm Infants with RDS

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Issue Date
2012-05-29Author
Barlow, Steven M.
Burch, Mimi
Venkatesan, Lalit Kumar
Harold, Meredith
Zimmerman, Emily
Publisher
Hindawi Publishing Corporation
Type
Article
Article Version
Scholarly/refereed, publisher version
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Show full item recordAbstract
The nonnutritive suck (NNS) is an observable and accessible motor behavior which is often used to make inference about brain development and pre-feeding skill in preterm and term infants. The purpose of this study was to model NNS burst compression pressure dynamics in the frequency and time domain among two groups of preterm infants, including those with respiratory distress syndrome (RDS, N=15) and 17 healthy controls. Digitized samples of NNS compression pressure waveforms recorded at a 1-week interval were collected 15 minutes prior to a scheduled feed. Regression analysis and ANOVA revealed that healthy preterm infants produced longer NNS bursts and the mean burst initiation cycle frequencies were higher when compared to the RDS group. Moreover, the initial 5 cycles of the NNS burst manifest a frequency modulated (FM) segment which is a significant feature of the suck central pattern generator (sCPG), and differentially expressed in healthy and RDS infants. The NNS burst structure revealed significantly lower spatiotemporal index values for control versus RDS preterm infants during FM, and provides additional information on the microstructure of the sCPG which may be used to gauge the developmental status and progression of oromotor control systems among these fragile infants.
Description
This is the published version, also available here: http://dx.doi.org/10.1155/2012/581538.
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Citation
Steven M. Barlow, Mimi Burch, Lalit Venkatesan, Meredith Harold, and Emily Zimmerman, “Frequency Modulation and Spatiotemporal Stability of the sCPG in Preterm Infants with RDS,” International Journal of Pediatrics, vol. 2012, Article ID 581538, 9 pages, 2012. http://dx.doi.org/10.1155/2012/581538.
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