Persistent nonmalignant pain management using nonsteroidal anti-inflammatory drugs in older patients and use of inappropriate adjuvant medications.

Rianon, Nahid; Knell, Maureen E.; Agbor-Bawa, Walter; Thelen, Joan; Burkhardt, Crystal; Rasu, Rafia

dc.contributor.author	Rianon, Nahid
dc.contributor.author	Knell, Maureen E.
dc.contributor.author	Agbor-Bawa, Walter
dc.contributor.author	Thelen, Joan
dc.contributor.author	Burkhardt, Crystal
dc.contributor.author	Rasu, Rafia
dc.date.accessioned	2015-03-03T22:29:03Z
dc.date.available	2015-03-03T22:29:03Z
dc.date.issued	2015-01-29
dc.identifier.citation	Rianon, et al. "Persistent nonmalignant pain management using nonsteroidal anti-inflammatory drugs in older patients and use of inappropriate adjuvant medications." Drug Healthc Patient Saf. 2015; 7: 43–50. Published online 2015 Jan 29. http://dx.doi.org/10.2147/DHPS.S67425	en_US
dc.identifier.uri	http://hdl.handle.net/1808/16961
dc.description.abstract	Objective Due to the high risk of life-threatening side effects, nonsteroidal anti-inflammatory drugs (NSAIDs) are not favored for treating persistent nonmalignant pain in the elderly. We report national prescription trends with determinants of NSAIDs prescription for persistent nonmalignant pain among older patients (age 65 and over) in the US outpatient setting. Methods A cross-sectional analysis was performed using National Ambulatory Medical Care Survey data. Prescriptions for NSAIDs, opioids, and adjuvant agents were identified using five-digit National Ambulatory Medical Care Survey drug codes. Results About 89% of the 206,879,848 weighted visits in the US from 2000 to 2007 recorded NSAIDs prescriptions in patients (mean age =75.4 years). Most NSAIDs users had Medicare (75%), and about 25% were prescribed with adjuvant medications considered inappropriate for their age. Compared to men, women were 1.79 times more likely to be prescribed NSAIDs. Conclusion The high percentage of NSAIDs prescription in older patients is alarming. We recommend investigating the appropriateness of the high prevalence of NSAIDs use among older patients reported in our study.	en_US
dc.description.sponsorship	Disclosure Part of the findings were presented as a poster at the American Geriatric Society (AGS) Annual Meeting in Seattle, WA held in May 2012. The authors report no conflicts of interest in this work.	en_US
dc.publisher	Dove Medical Press	en_US
dc.rights	© 2015 Rianon et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/
dc.subject	pain management	en_US
dc.subject	NSAIDs	en_US
dc.subject	inappropriate adjuvant	en_US
dc.subject	AGS guideline	en_US
dc.subject	NAMCS	en_US
dc.title	Persistent nonmalignant pain management using nonsteroidal anti-inflammatory drugs in older patients and use of inappropriate adjuvant medications.	en_US
dc.type	Article
kusw.kuauthor	Agbor-Bawa, Walter
kusw.kuauthor	Burkhardt, Crystal
kusw.kuauthor	Rasu, Rafia
kusw.kudepartment	Department of Pharmacy	en_US
dc.identifier.doi	10.2147/DHPS.S67425
dc.identifier.orcid	https://orcid.org/0000-0003-1802-9111
kusw.oaversion	Scholarly/refereed, publisher version
kusw.oapolicy	This item meets KU Open Access policy criteria.
dc.rights.accessrights	openAccess

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