ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
Autosomal short tandem repeat genetic variation of the Basques in Spain
dc.contributor.author | Young, Kristin Leigh | |
dc.contributor.author | Sun, Guangyun | |
dc.contributor.author | Deka, Ranjan | |
dc.contributor.author | Crawford, Michael H. | |
dc.date.accessioned | 2014-04-15T14:23:14Z | |
dc.date.available | 2014-04-15T14:23:14Z | |
dc.date.issued | 2011-06 | |
dc.identifier.citation | Young, Kristin L, Guangyun Sun, Ranjan Deka, and Michael H Crawford. 2011. “Autosomal Short Tandem Repeat Genetic Variation of the Basques in Spain.” Croatian Medical Journal 52 (3): 372–83. http://dx.doi.org/10.3325/cmj.2011.52.372 | |
dc.identifier.uri | http://hdl.handle.net/1808/13487 | |
dc.description.abstract | AimTo examine population genetic structure and hypotheses of the origin of the modern Basque population in Spain using autosomal short tandem repeat (STR) data from individuals living in 27 mountain villages in the provinces of Alava, Vizcaya, Guipuzcoa, and Navarre, by comparing Basque autosomal STR variation with that of neighboring populations in Europe, as well as proposed ancestral populations in North Africa and the Caucasus. MethodsAllele frequencies for 9 autosomal STR loci (D3S1358, D5S818, D7S820, D8S1179, D13S317, D18S51, D21S11, FGA, and vWA) and several population genetic parameters were determined for the 4 provinces in the Basque region of Spain (n = 377). Heterozygosity within the Basque population was measured using a locus-by-locus analysis of molecular variance. Relationships between the Basques and other populations were examined using a multidimensional scaling (MDS) plot of Shriver’s DSW distance matrix. ResultsHeterozygosity levels in the Basque provinces were on the low end of the European distribution (0.805-0.812). The MDS plot of genetic distances revealed that the Basques differed from both the Caucasian and North African populations with respect to autosomal STR variation. ConclusionsAutosomal STR analysis does not support the hypotheses of a recent common ancestor between the Basques and populations either from the Caucasus or North Africa. | |
dc.description.sponsorship | Funding This work is supported in part by National Geographic Society Grant (Project 6935-00) to the University of Kansas Laboratory of Biological Anthropology. | |
dc.publisher | Croatian Medical Journal | |
dc.rights | This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | Autosomal short tandem repeat genetic variation of the Basques in Spain | |
dc.type | Article | |
kusw.kuauthor | Crawford, Michael H. | |
kusw.kudepartment | Department of Anthroplogy | |
dc.identifier.doi | 10.3325/cmj.2011.52.372 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |
Files in this item
This item appears in the following Collection(s)
-
Anthropology Scholarly Works [206]
-
Center for Russian, East European, and Eurasian Studies Scholarly Publications [546]
This collection contains publications by faculty affiliated with CREES.