Phylogenetic assessment of filoviruses: how many lineages of Marburg virus?
Issue Date
2012-07-01Author
Peterson, A. Townsend
Holder, Mark T.
Publisher
Wiley Open Access
Type
Article
Article Version
Scholarly/refereed, publisher version
Metadata
Show full item recordAbstract
Filoviruses have to date been considered as consisting of one diverse genus (Ebola viruses) and one undifferentiated genus (Marburg virus). We reconsider this idea by means of detailed phylogenetic analyses of sequence data available for the Filoviridae: using coalescent simulations, we ascertain that two Marburg isolates (termed the “RAVN” strain) represent a quite-distinct lineage that should be considered in studies of biogeography and host associations, and may merit recognition at the level of species. In contrast, filovirus isolates recently obtained from bat tissues are not distinct from previously known strains, and should be considered as drawn from the same population. Implications for understanding the transmission geography and host associations of these viruses are discussed.
Description
This is the publisher's version, also available electronically from http://onlinelibrary.wiley.com.
ISSN
2045-7758Collections
Citation
Peterson, A. Townsend; Holder, Mark T. Phylogenetic assessment of filoviruses: how many lineages of Marburg virus? 2012. Ecology and Evolution 2(8):1826-1833. http://dx.doi.org/10.1002/ece3.297
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