Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites.
| dc.contributor.author | Burrow, Allison A. | |
| dc.contributor.author | Williams, Laura E. | |
| dc.contributor.author | Pierce, Levi C. T. | |
| dc.contributor.author | Wang, Yuh-Hwa | |
| dc.date.accessioned | 2014-01-17T18:29:55Z | |
| dc.date.available | 2014-01-17T18:29:55Z | |
| dc.date.issued | 2009-01-30 | |
| dc.identifier.citation | Burrow, Allison A, Laura E Williams, Levi C T Pierce, and Yuh-Hwa Wang. 2009. “Over Half of Breakpoints in Gene Pairs Involved in Cancer-Specific Recurrent Translocations Are Mapped to Human Chromosomal Fragile Sites.” BMC Genomics 10: 59. http://dx.doi.org/10.1186/1471-2164-10-59 | |
| dc.identifier.uri | http://hdl.handle.net/1808/12765 | |
| dc.description.abstract | Gene rearrangements such as chromosomal translocations have been shown to contribute to cancer development. Human chromosomal fragile sites are regions of the genome especially prone to breakage, and have been implicated in various chromosome abnormalities found in cancer. However, there has been no comprehensive and quantitative examination of the location of fragile sites in relation to all chromosomal aberrations. | |
| dc.language.iso | en | |
| dc.publisher | BioMed Central | |
| dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
| dc.rights.uri | http://creativecommons.org/licenses/by/2.0 | |
| dc.title | Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites. | |
| dc.type | Article | |
| kusw.kuauthor | Pierce, Levi C. | |
| kusw.kudepartment | Department of Electrical Engineering and Computer Science | |
| kusw.oastatus | fullparticipation | |
| dc.identifier.doi | 10.1186/1471-2164-10-59 | |
| kusw.oaversion | Scholarly/refereed, publisher version | |
| kusw.oapolicy | This item meets KU Open Access policy criteria. | |
| dc.rights.accessrights | openAccess |
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