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Dissertations and Theses: Recent submissions
Now showing items 2121-2140 of 9900
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A COMPARATIVE STUDY OF ENGLISH SECOND LANGUAGE READING COMPREHENSION OF A RELIGION-BASED ASSESSMENT IN TWO DIFFERENT LOCATIONAL CONTEXTS
(University of Kansas, 2018-08-31)ABSTRACT A Comparative Study of English Second Language Reading Comprehension of a Religion-Based Assessment in Two Different Locational Contexts This study examined two different educational locations which had distinct ... -
Demobilization in Morocco: The Case of The February 20 Movement
(University of Kansas, 2018-08-31)This dissertation aims to understand why protests lessen when they do by investigating how and why social movements demobilize. I do this by questioning the causal link between consistent state polices (concessions or ... -
Noise Exposure, Self-Reported Speech-in-Noise Percpetion, and the Auditory Brainstem Response in Normal-Hearing Human Ears
(University of Kansas, 2018-08-31)Difficulty understanding speech-in-noise (SIN) is a common complaint among many listeners. There is emerging evidence that noise exposure is associated with difficulties in speech discrimination and temporal processing ... -
Gender and the Green Economy
(University of Kansas, 2018-08-31)The Green Economy is supposed to be sustainable but is it? Being sustainable would entail being equitable. Feminist scholarship shows that the mainstream economy is thoroughly organized by gender, is inequitable, and ... -
The Persistence of Advertising Culture: Commerce and Consumers in Multi-Ethnic Galicia, 1911-1921
(University of Kansas, 2018-12-31)Despite tremendous change and instability during the second decade of the twentieth century due to modernization, war, and political reconfiguration, some elements of everyday life in Cracow and Lemberg maintained a ... -
Chemical and Physical Instability of Monoclonal Antibodies Induced by Metal-catalyzed Carbonylation
(University of Kansas, 2019-05-31)In the pharmaceutical industry, recombinant monoclonal antibodies (mAbs) have become a major focus of therapeutic drug development due to their broad applications in many disease areas. During manufacturing and storage of ... -
Utilizing IgG1 Fc As An Immunomodulator
(University of Kansas, 2019-05-31)Antibody-based therapeutics are a rapidly expanding class of biopharmaceuticals. The number of approved antibody-based therapeutics by the FDA and EMA has more than doubled in the last five years, and they are expanding ... -
Strategies for the Fluorine-Retentive Functionalization of Gem-Difluoroalkenes
(University of Kansas, 2019-05-31)Fluorination is an important strategy for perturbing the biophysical properties of compounds in medicinal chemistry. Specifically, fluorination modulates both the pharmacodynamic and pharmacokinetic properties of bioactive ... -
Cyclophilin D as a potential therapeutic target for Alzheimer’s disease
(University of Kansas, 2019-05-31)Alzheimer’s disease (AD) is the sixth leading cause of death in United States, affecting more than five million people every year. Despite substantial research into the topic, including over a hundred thousand research ... -
The Degradation of 4-Morpholinoaniline in Aqueous Solution
(University of Kansas, 2019-05-31)The reactivity of 4-morpholinoaniline with water was examined in aqueous solutions at pH 1 – 4. Two dissociation constant values were identified for 4-morpholinoaniline using spectrophotometric titration: pKa1, which was ... -
Studies of novel targeted drug delivery systems and molecular probes of cancer biology
(University of Kansas, 2019-05-31)Cancer is a complex family of diseases. As our understanding of cancer biology has improved, so has our ability to treat the pathology associated with this condition. Traditional anticancer therapeutics lack selectivity ... -
Characterization, Stabilization and Formulation Design of IgG and Secretory IgA Monoclonal Antibody Candidates during Storage and Administration
(University of Kansas, 2019-05-31)ABSTRACT Monoclonal antibodies (mAbs) have become a class of therapeutic protein-based drugs of high importance for treating numerous human diseases. As a complex, delicate three dimensional molecule, a mAb can be sensitive ... -
Targeted Proteomics for Exosome Analysis and Its Application to Develop Blood Markers of Liver Drug-Metabolizing Enzymes
(University of Kansas, 2019-05-31)Two main routes of drug elimination include renal excretion via the kidney and metabolic degradation via metabolizing enzymes (DMEs) in the liver, followed by renal excretion or biliary elimination of the now more polar ... -
Experimental and Analytical Procedures to Characterize Mechanical Properties of Asphalt Concrete Materials for Airfield Pavement Applications
(University of Kansas, 2018-12-31)In the past two decades, the pavement mechanics community have made a significant progress in developing mechanistic-based constitutive relationships for asphalt concrete materials, flexible airfield pavements, and roadways. ... -
Experimental and numerical investigations of shale gas permeability
(University of Kansas, 2018-12-31)Shale gas has become an essential source of energy supply in the United States and the world. It is important to analyze shale gas flow behavior and the associated production behavior from experimental and simulation ... -
AN ONLINE TOOLKIT TO IMPROVE PRIMARY CARE PROVIDER IDENTIFICATION OF NON-ALCOHOLIC FATTY LIVER DISEASE
(University of Kansas, 2019-05-31)Non-alcoholic fatty liver disease (NAFLD) prevalence has reached epidemic proportions and the severe type, non-alcoholic steatohepatitis (NASH) is predicted to become the leading cause of liver transplant over the next two ... -
An Analysis of Group Prenatal Care in a High-Risk Obstetric Population
(University of Kansas, 2019-05-31)Abstract Problem: Preterm birth and low birth weight (LBW) are the second leading causes of infant mortality after birth defects. In 1985, an expert panel from the Institute of Medicine concluded that prenatal care services ... -
LGBTQ Adolescent Smoking: A Social Media Approach to Primary Prevention
(University of Kansas, 2019-05-31)Objective This paper briefly reviews the literature about increased smoking among lesbian, gay, bisexual, transgender, and queer (LGBTQ) adolescents and evaluates both the deployment of a primary smoking prevention ... -
Parental Education and HPV Vaccination Intent
(University of Kansas, 2019-05-31)Abstract The human papillomavirus (HPV) is responsible for 99% of cervical cancers and a large number of cancers, including vulvar, vaginal, oropharyngeal, anal and penile cancers. An HPV vaccine was introduced in the ... -
Exploring the Impact of an Elective Joint Replacement Care Pathway in a Safety-Net Hospital: Ongoing Quality Improvement
(University of Kansas, 2019-05-31)One of the innovative ways that organizations have tried to bridge the gap between quality and cost is with the implementation of care pathways. Truman Medical Center (TMC), a safety-net hospital, has implemented a ...