KUKU

KU ScholarWorks

  • myKU
  • Email
  • Enroll & Pay
  • KU Directory
    • Login
    View Item 
    •   KU ScholarWorks
    • Dissertations and Theses
    • Dissertations
    • View Item
    •   KU ScholarWorks
    • Dissertations and Theses
    • Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    NEURAL PROCESSING OF EMOTIONAL MUSIC AND SOUNDS IN DEPRESSION

    Thumbnail
    View/Open
    Lepping_ku_0099D_12646_DATA_1.pdf (3.860Mb)
    Issue Date
    2013-05-31
    Author
    Lepping, Rebecca Jo Chambers
    Publisher
    University of Kansas
    Format
    133 pages
    Type
    Dissertation
    Degree Level
    Ph.D.
    Discipline
    Psychology
    Rights
    This item is protected by copyright and unless otherwise specified the copyright of this thesis/dissertation is held by the author.
    Metadata
    Show full item record
    Abstract
    The present study uses functional MRI and an emotional sound and music paradigm to examine how neural processing of emotionally provocative auditory stimuli is altered in depression. Functional MRI was used to localize the neural response to auditory emotional stimulation, hypothesized to differ between depressed and never-depressed control participants in brain regions known to be involved in reward processing and rumination. Twenty individuals with depression (MDD) and 18 controls (ND) listened to positive and negative emotional musical and nonmusical stimuli during fMRI scanning, and gave subjective ratings of valence and arousal following scanning. ND participants exhibited greater activation to positive versus negative stimuli in the ventral anterior cingulate cortex (vACC), dorsal amygdala, and hippocampus, regions known to be affected in depression. They also showed two distinct processing networks for music versus sounds, with music activating the default mode network (DMN) and sounds activating object identification regions to a greater extent. When compared with control participants, depressed participants showed a different pattern of activation to these emotional stimuli in the ACC. In the rostral part of the ACC, ND participants showed greater activation for positive information, while MDD participants showed greater activation to negative information. In the dorsal and perigenual ACC, the pattern of activation distinguished between the types of sounds, with ND showing greater activation to music compared to sounds, while MDD showed greater activation to sounds, with the greatest response to negative sounds. The anterior cingulate is critical for emotion processing and functions as a relay for diverting cognitive control to demanding tasks. These results suggest that the type of auditory stimulation, as well as the emotional content may be processed differently by people with depression.
    URI
    http://hdl.handle.net/1808/12330
    Collections
    • Dissertations [4660]
    • Psychology Dissertations and Theses [459]

    Items in KU ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.


    We want to hear from you! Please share your stories about how Open Access to this item benefits YOU.


    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

    Browse

    All of KU ScholarWorksCommunities & CollectionsThis Collection

    My Account

    Login

    Statistics

    View Usage Statistics

    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

    The University of Kansas
      Contact KU ScholarWorks
    Lawrence, KS | Maps
     
    • Academics
    • Admission
    • Alumni
    • Athletics
    • Campuses
    • Giving
    • Jobs

    The University of Kansas prohibits discrimination on the basis of race, color, ethnicity, religion, sex, national origin, age, ancestry, disability, status as a veteran, sexual orientation, marital status, parental status, gender identity, gender expression and genetic information in the University’s programs and activities. The following person has been designated to handle inquiries regarding the non-discrimination policies: Director of the Office of Institutional Opportunity and Access, IOA@ku.edu, 1246 W. Campus Road, Room 153A, Lawrence, KS, 66045, (785)864-6414, 711 TTY.

     Contact KU
    Lawrence, KS | Maps