Myosin heavy chain isoform expression: Influence on isointertial and isometric performance
Issue Date
2005Author
Schilling, Brian K.
Fry, Andrew C.
Weiss, Lawrence W.
Chiu, Loren Z. F.
Publisher
Taylor & Francis
Type
Article
Article Version
Scholarly/refereed, publisher version
Published Version
http://ehis.ebscohost.com/ehost/detail?vid=3&sid=c184ec76-77d8-4a98-bb1f-f5bceba902aa%40sessionmgr10&hid=2&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=s3h&AN=19495568Metadata
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Thirty-six healthy men with varying degrees of physical training background performed maximal-effort isometric and isoinertial knee extensor actions, with relative loads equal to 40% and 70% of one-repetition maximum. Force, velocity, and power were derived from force and linear position transducers at 500 Hz. Biopsies were taken from the vastus lateralis and analyzed by SDS-PAGE for relative myosin heavy chain (MHC) content. Relative MHC IIx content was included in a regression model, and explained variance noted. Relative MHC I content was subsequently added to the regression model to determine what, if any, additional variance was explained beyond that of MHC IIx. Results indicated that no relationship ( r = 0.0 to 0.1) exists between the relative expression of MHC isoforms from the vastus lateralis and isometric/isoinertial performance in a population with diverse training backgrounds. Lack of nervous system adaptations in the untrained subjects in the study possibly attenuates the significant relationship between MHC and in-vivo muscle performance previously established in trained populations. ABSTRACT FROM AUTHOR
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This is the publisher's version, also found at http://ehis.ebscohost.com/ehost/detail?vid=3&sid=c184ec76-77d8-4a98-bb1f-f5bceba902aa%40sessionmgr10&hid=2&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#db=s3h&AN=19495568
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Citation
Schilling, Brian K.; Fry, Andrew C.; Weiss, Lawrence W.; and Chiu, Loren Z. F. (2008) Myosin heavy chain isoform expression: Influence on isointertial and isometric performance. Research in Sports Medicine: An International Journal, 13: 301-315.
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