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Rehabilitation in People Living with Glioblastoma: A Narrative Review of the Literature

Boele, Florien W.
Zanotto, Tobia
Glover, Rebecca N.
Zanotto, Anna
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Abstract
Glioblastoma is the most common primary malignant brain tumor. While preliminary data point to the positive effects of rehabilitation for patients with glioblastoma, there are unique challenges for clinicians working with this population, including limited life expectancy and/or rapid neurological deterioration. The aim of this article is to review the literature on rehabilitation of adults with glioblastoma, including the feasibility of interventions, their effectiveness, as well as the current clinical practice. The reviewed literature suggests that rehabilitation has been found beneficial for improving the functional prognosis and quality of life of adults with glioblastoma and is desired by patients. We summarize the qualitative evidence regarding healthcare professionals’ and patients’ perspectives on the use of supportive care services. We conclude there is a need for the design of effective rehabilitation programs for patients with glioblastoma, as well as for the development of glioblastoma-specific clinical guidelines for rehabilitation practitioners. Keywords: glioblastoma; neuro-oncology; quality of life; rehabilitation; occupational therapy; physical therapy; cognitive rehabilitation
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A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.
Date
2024-04-27
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Zanotto, A.; Glover, R.N.; Zanotto, T.; Boele, F.W. Rehabilitation in People Living with Glioblastoma: A Narrative Review of the Literature. Cancers 2024, 16, 1699. https://doi.org/10.3390/cancers16091699
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