Covalent Tethers for Precise Amino Alcohol Syntheses: Ring Opening of Epoxides by Pendant Sulfamates and Sulfamides

Nagamalla, Someshwar; Mague, Joel T.; Sathyamoorthi, Shyam

dc.contributor.author	Nagamalla, Someshwar
dc.contributor.author	Mague, Joel T.
dc.contributor.author	Sathyamoorthi, Shyam
dc.date.accessioned	2023-06-13T20:54:06Z
dc.date.available	2023-06-13T20:54:06Z
dc.date.issued	2023-02-06
dc.identifier.citation	Nagamalla, S., Mague, J. T., & Sathyamoorthi, S. (2023). Covalent Tethers for Precise Amino Alcohol Syntheses: Ring Opening of Epoxides by Pendant Sulfamates and Sulfamides. Organic letters, 25(6), 982–986. https://doi.org/10.1021/acs.orglett.3c00053	en_US
dc.identifier.uri	https://hdl.handle.net/1808/34375
dc.description	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, Copyright © 2023 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.3c00053.	en_US
dc.description.abstract	We describe the development of the first ring opening of epoxides using pendant sulfamates and sulfamides. These reactions are promoted by a base and proceed under mild conditions to afford oxathiazinanes and cyclic sulfamides with excellent diastereoselectivity and regiocontrol. The reactions scale well, and the products serve as synthons for ring-opening reactions.	en_US
dc.publisher	American Chemical Society	en_US
dc.rights	Copyright © 2023 American Chemical Society	en_US
dc.subject	Cyclization	en_US
dc.subject	Ethers	en_US
dc.subject	Mixtures	en_US
dc.subject	Ring opening reactions	en_US
dc.subject	Substitution reactions	en_US
dc.title	Covalent Tethers for Precise Amino Alcohol Syntheses: Ring Opening of Epoxides by Pendant Sulfamates and Sulfamides	en_US
dc.type	Article	en_US
kusw.kuauthor	Nagamalla, Someshwar
kusw.kuauthor	Sathyamoorthi, Shyam
kusw.kudepartment	Medicinal Chemistry	en_US
dc.identifier.doi	10.1021/acs.orglett.3c00053	en_US
dc.identifier.orcid	https://orcid.org/0000-0003-4705-7349	en_US
kusw.oaversion	Scholarly/refereed, author accepted manuscript	en_US
kusw.oapolicy	This item meets KU Open Access policy criteria.	en_US
dc.identifier.pmid	PMC10017054	en_US
dc.rights.accessrights	embargoedAccess	en_US

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